{"id":1905,"date":"2019-05-29T22:32:09","date_gmt":"2019-05-29T12:32:09","guid":{"rendered":"https:\/\/www.cognav.net\/?p=1905"},"modified":"2019-05-29T22:32:09","modified_gmt":"2019-05-29T12:32:09","slug":"neural-dynamics-indicate-parallel-integration-of-environmental-and-self-motion-information-by-place-and-grid-cells","status":"publish","type":"post","link":"https:\/\/braininspirednavigation.com\/?p=1905","title":{"rendered":"Neural dynamics indicate parallel integration of environmental and self-motion information by place and grid cells"},"content":{"rendered":"<p style=\"text-align: justify;\">Laptev, Dmitri, and Neil Burgess. &#8220;<a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/640144v1\"><strong>Neural dynamics indicate parallel integration of environmental and self-motion information by place and grid cells<\/strong><\/a>.&#8221;\u00a0<i>bioRxiv<\/i>\u00a0(2019): 640144.<\/p>\n<p style=\"text-align: justify;\">Abstract<br \/>\nPlace cells and grid cells in the hippocampal formation are thought to integrate sensory and self-motion information into a representation of estimated spatial location,<span style=\"color: #ff0000;\"><strong> but the precise mechanism is unknown<\/strong><\/span>. <strong><span style=\"color: #ff0000;\">We simulated a parallel attractor system in which place cells form an attractor network driven by environmental inputs and grid cells form an attractor network performing path integration driven by self-motion, with inter-connections between them allowing both types of input to influence firing in both ensembles<\/span><\/strong>. We show that such a system is needed to explain the spatial patterns and temporal dynamics of place cell firing when rats run on a linear track in which the familiar correspondence between environmental and self-motion inputs is changed (Gothard et al., 1996b; Redish et al., 2000). In contrast, the alternative architecture of a single recurrent network of place cells (performing path integration and receiving environmental inputs) cannot reproduce the place cell firing dynamics. <strong><span style=\"color: #ff0000;\">These results support the hypothesis that grid and place cells provide two different but complementary attractor representations (based on self-motion and environmental sensory inputs respectively). Our results also indicate the specific neural mechanism and main predictors of hippocampal map realignment and make predictions for future studies.<\/span><\/strong><\/p>\n<p>Laptev, Dmitri, and Neil Burgess. &#8220;<a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/640144v1\"><strong>Neural dynamics indicate parallel integration of environmental and self-motion information by place and grid cells<\/strong><\/a>.&#8221;\u00a0<i>bioRxiv<\/i>\u00a0(2019): 640144.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Laptev, Dmitri, and Neil Burgess. &#8220;Neural dynamics indicate parallel integration of environmental and self-motion information by place and grid cells.&#8221;\u00a0bioRxiv\u00a0(2019): 640144. Abstract Place cells and grid cells in the hippocampal formation are thought to integrate sensory and self-motion information into a representation of estimated spatial location, but the precise mechanism is unknown. We simulated a [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[96,346],"tags":[98,367,492,292,97],"_links":{"self":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/1905"}],"collection":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1905"}],"version-history":[{"count":1,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/1905\/revisions"}],"predecessor-version":[{"id":1906,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/1905\/revisions\/1906"}],"wp:attachment":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1905"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1905"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1905"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}