{"id":1949,"date":"2019-06-29T20:30:51","date_gmt":"2019-06-29T10:30:51","guid":{"rendered":"https:\/\/www.cognav.net\/?p=1949"},"modified":"2019-06-29T20:30:51","modified_gmt":"2019-06-29T10:30:51","slug":"whether-entorhinal-velocity-signals-are-equally-influenced-or-provide-a-universal-metric-for-self-motion-across-environments-2","status":"publish","type":"post","link":"https:\/\/braininspirednavigation.com\/?p=1949","title":{"rendered":"Whether entorhinal velocity signals are equally influenced or provide a universal metric for self-motion across environments?"},"content":{"rendered":"<p style=\"text-align: justify;\">Munn, Robert GK, Caitlin S. Mallory, Kiah Hardcastle, Dane M. Chetkovich, and Lisa M. Giocomo. &#8220;<a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/671222v1\"><strong>Entorhinal velocity signals reflect environmental geometry<\/strong><\/a>.&#8221; bioRxiv (2019): 671222.\u00a0<span class=\"label\">doi:<\/span>\u00a0https:\/\/doi.org\/10.1101\/671222<\/p>\n<p style=\"text-align: justify;\">Summary<br \/>\n<strong><span style=\"color: #ff0000;\">The entorhinal cortex contains neural signals for representing self-location, including grid cells that fire in periodic locations and velocity signals that encode an animal\u2019s speed and head direction.<\/span><\/strong> Recent work revealed that the size and shape of the environment influences grid patterns. <strong><span style=\"color: #ff0000;\">Whether entorhinal velocity signals are equally influenced or provide a universal metric for self-motion across environments remains unknown.<\/span> <\/strong>Here, we report that changes to the size and shape of the environment result in re-scaling in entorhinal speed codes. Moreover, head direction cells re-organize in an experience-dependent manner to align with the axis of environmental change. A knockout mouse model allows a dissociation of the coordination between cell types, with grid and speed, but not head direction, cells responding in concert to environmental change. <strong><span style=\"color: #ff0000;\">These results align with predictions of grid cell attractor models and point to inherent flexibility in the coding features of multiple functionally-defined entorhinal cell types<\/span><\/strong>.<\/p>\n<p style=\"text-align: justify;\">Munn, Robert GK, Caitlin S. Mallory, Kiah Hardcastle, Dane M. Chetkovich, and Lisa M. Giocomo. &#8220;<a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/671222v1\"><strong>Entorhinal velocity signals reflect environmental geometry<\/strong><\/a>.&#8221; bioRxiv (2019): 671222.\u00a0<span class=\"label\">doi:<\/span>\u00a0https:\/\/doi.org\/10.1101\/671222<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Munn, Robert GK, Caitlin S. Mallory, Kiah Hardcastle, Dane M. Chetkovich, and Lisa M. Giocomo. &#8220;Entorhinal velocity signals reflect environmental geometry.&#8221; bioRxiv (2019): 671222.\u00a0doi:\u00a0https:\/\/doi.org\/10.1101\/671222 Summary The entorhinal cortex contains neural signals for representing self-location, including grid cells that fire in periodic locations and velocity signals that encode an animal\u2019s speed and head direction. Recent work [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[96,346],"tags":[103,511,512],"_links":{"self":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/1949"}],"collection":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1949"}],"version-history":[{"count":1,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/1949\/revisions"}],"predecessor-version":[{"id":1950,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/1949\/revisions\/1950"}],"wp:attachment":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1949"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1949"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1949"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}