{"id":1981,"date":"2019-07-08T14:58:33","date_gmt":"2019-07-08T04:58:33","guid":{"rendered":"https:\/\/www.cognav.net\/?p=1981"},"modified":"2019-07-08T14:58:33","modified_gmt":"2019-07-08T04:58:33","slug":"how-the-brain-remembers-where-youre-heading-to","status":"publish","type":"post","link":"https:\/\/braininspirednavigation.com\/?p=1981","title":{"rendered":"How the brain remembers where you\u2019re heading to?"},"content":{"rendered":"<p style=\"text-align: justify;\">Kunz, Lukas, Liang Wang, Daniel Lachner-Piza, Hui Zhang, Armin Brandt, Matthias D\u00fcmpelmann, Peter C. Reinacher et al. <a href=\"https:\/\/advances.sciencemag.org\/content\/5\/7\/eaav8192\"><strong>&#8220;Hippocampal theta phases organize the reactivation of large-scale electrophysiological representations during goal-directed navigation.&#8221;<\/strong><\/a> Science Advances 5, no. 7 (2019): eaav8192.<\/p>\n<p style=\"text-align: justify;\">Abstract<br \/>\n<strong><span style=\"color: #ff0000;\">Humans are adept in simultaneously following multiple goals, but the neural mechanisms for maintaining specific goals and distinguishing them from other goals are incompletely understood.<\/span><\/strong> For short time scales, working memory studies suggest that multiple mental contents are maintained by theta-coupled reactivation, but evidence for similar mechanisms during complex behaviors such as goal-directed navigation is scarce. We examined intracranial electroencephalography recordings of epilepsy patients performing an object-location memory task in a virtual environment. We report that large-scale electrophysiological representations of objects that cue for specific goal locations are dynamically reactivated during goal-directed navigation. <strong><span style=\"color: #ff0000;\">Reactivation of different cue representations occurred at stimulus-specific hippocampal theta phases. Locking to more distinct theta phases predicted better memory performance, identifying hippocampal theta phase coding as a mechanism for separating competing goals.<\/span> <span style=\"color: #ff0000;\">Our findings suggest shared neural mechanisms between working memory and goal-directed navigation and provide new insights into the functions of the hippocampal theta rhythm.<\/span><\/strong><\/p>\n<p style=\"text-align: justify;\">Further info, please read the paper\u00a0Kunz et al. 2019<\/p>\n<p style=\"text-align: justify;\">Kunz, Lukas, Liang Wang, Daniel Lachner-Piza, Hui Zhang, Armin Brandt, Matthias D\u00fcmpelmann, Peter C. Reinacher et al. <a href=\"https:\/\/advances.sciencemag.org\/content\/5\/7\/eaav8192\"><strong>&#8220;Hippocampal theta phases organize the reactivation of large-scale electrophysiological representations during goal-directed navigation.&#8221;<\/strong><\/a> Science Advances 5, no. 7 (2019): eaav8192.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Kunz, Lukas, Liang Wang, Daniel Lachner-Piza, Hui Zhang, Armin Brandt, Matthias D\u00fcmpelmann, Peter C. Reinacher et al. &#8220;Hippocampal theta phases organize the reactivation of large-scale electrophysiological representations during goal-directed navigation.&#8221; Science Advances 5, no. 7 (2019): eaav8192. Abstract Humans are adept in simultaneously following multiple goals, but the neural mechanisms for maintaining specific goals and [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[96,346,419,519],"tags":[460,521,522],"_links":{"self":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/1981"}],"collection":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1981"}],"version-history":[{"count":1,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/1981\/revisions"}],"predecessor-version":[{"id":1982,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/1981\/revisions\/1982"}],"wp:attachment":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1981"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1981"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1981"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}