{"id":1991,"date":"2019-07-13T11:13:59","date_gmt":"2019-07-13T01:13:59","guid":{"rendered":"https:\/\/www.cognav.net\/?p=1991"},"modified":"2019-12-02T20:06:45","modified_gmt":"2019-12-02T10:06:45","slug":"how-does-rat-place-cells-encode-3d-volumetric-space","status":"publish","type":"post","link":"https:\/\/braininspirednavigation.com\/?p=1991","title":{"rendered":"How does rat place cells encode 3D volumetric space?"},"content":{"rendered":"<p style=\"text-align: justify;\">Roddy M Grieves, Selim Jedidi-Ayoub, Karyna Mishchanchuk, Anyi Liu, Sophie Renaudineau, Kate J Jeffery.\u00a0<a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/698175v1\"><strong>The place-cell representation of volumetric space in rats<\/strong><\/a>. <span class=\"highwire-cite-metadata-journal highwire-cite-metadata\">bioRxiv\u00a0<\/span><span class=\"highwire-cite-metadata-pages highwire-cite-metadata\">698175;\u00a0<\/span><span class=\"highwire-cite-metadata-doi highwire-cite-metadata\"><span class=\"doi_label\">doi:<\/span>\u00a0https:\/\/doi.org\/10.1101\/698175<\/span><\/p>\n<p style=\"text-align: justify;\">Abstract<br \/>\n&#8220;Place cells are spatially modulated neurons found in the hippocampus that underlie spatial memory and navigation: <strong><span style=\"color: #ff0000;\">how these neurons represent 3D space is largely unknown<\/span><\/strong>. We wirelessly recorded place cells in rats at they explored a cubic lattice climbing frame which could be aligned or tilted with respect to gravity. <strong><span style=\"color: #ff0000;\">Place cells represented the entire volume of the mazes: the activity of these cells tended to be aligned with the maze axes, and when it was more difficult for the animals to move vertically the cells represented space less accurately and less stably<\/span><\/strong>. These results demonstrate that <strong><span style=\"color: #ff0000;\">surface dwelling animals also represent 3D space and suggests there is a fundamental relationship between environment structure, gravity, movement and spatial memory<\/span><\/strong>. &#8220;<\/p>\n<p style=\"text-align: justify;\">Roddy M Grieves, Selim Jedidi-Ayoub, Karyna Mishchanchuk, Anyi Liu, Sophie Renaudineau, Kate J Jeffery.\u00a0<a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/698175v1\"><strong>The place-cell representation of volumetric space in rats<\/strong><\/a>. <span class=\"highwire-cite-metadata-journal highwire-cite-metadata\">bioRxiv\u00a0<\/span><span class=\"highwire-cite-metadata-pages highwire-cite-metadata\">698175;\u00a0<\/span><span class=\"highwire-cite-metadata-doi highwire-cite-metadata\"><span class=\"doi_label\">doi:<\/span>\u00a0https:\/\/doi.org\/10.1101\/698175<\/span><\/p>\n<p>All main text and supplementary figures and videos in high-resolution, zipped or mp4 format can be downloaded at <a href=\"https:\/\/rdr.ucl.ac.uk\/articles\/Grieves_et_al_2019_The_place-cell_representation_of_volumetric_space_in_rats_All_main_text_and_supplementary_figures_and_videos_in_high-resolution_zipped_or_mp4_format_\/9977435\">UCL website<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Roddy M Grieves, Selim Jedidi-Ayoub, Karyna Mishchanchuk, Anyi Liu, Sophie Renaudineau, Kate J Jeffery.\u00a0The place-cell representation of volumetric space in rats. bioRxiv\u00a0698175;\u00a0doi:\u00a0https:\/\/doi.org\/10.1101\/698175 Abstract &#8220;Place cells are spatially modulated neurons found in the hippocampus that underlie spatial memory and navigation: how these neurons represent 3D space is largely unknown. We wirelessly recorded place cells in rats [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[390,389,96,346],"tags":[120,530,531],"_links":{"self":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/1991"}],"collection":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1991"}],"version-history":[{"count":3,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/1991\/revisions"}],"predecessor-version":[{"id":2113,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/1991\/revisions\/2113"}],"wp:attachment":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1991"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1991"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1991"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}