{"id":2043,"date":"2019-10-26T09:44:45","date_gmt":"2019-10-25T23:44:45","guid":{"rendered":"https:\/\/www.cognav.net\/?p=2043"},"modified":"2019-10-26T09:44:45","modified_gmt":"2019-10-25T23:44:45","slug":"whether-the-firing-associations-of-grid-cells-depend-on-hippocampal-inputs-2","status":"publish","type":"post","link":"https:\/\/braininspirednavigation.com\/?p=2043","title":{"rendered":"Whether the firing associations of grid cells depend on hippocampal inputs?"},"content":{"rendered":"<p style=\"text-align: justify;\">Noam Almog, Gilad Tocker, Tora Bonnevie, Edvard Moser, May-Britt Moser, Dori Derdikman. <a href=\"https:\/\/elifesciences.org\/articles\/47147\"><strong>During hippocampal inactivation, grid cells maintain their synchrony, even when the grid pattern is lost<\/strong><\/a>.\u00a0eLife 2019;8:e47147 DOI: 10.7554\/eLife.47147<\/p>\n<p style=\"text-align: justify;\"><strong>Abstract<\/strong>\u00a0&#8220;The grid cell network in the medial entorhinal cortex (MEC) has been subject to thorough testing and analysis, and many theories for their formation have been suggested. To test some of these theories, we re-analyzed data from Bonnevie et al., 2013, in which the hippocampus was inactivated and grid cells were recorded in the rat MEC. <span style=\"color: #ff0000;\"><strong>We investigated whether the firing\u00a0<\/strong><\/span><span style=\"color: #ff0000;\"><strong>associations of grid cells depend on hippocampal inputs<\/strong><\/span>. Specifically, we examined <strong><span style=\"color: #ff0000;\">temporal and\u00a0<\/span><\/strong><strong><span style=\"color: #ff0000;\">spatial correlations<\/span><\/strong> in the firing times of simultaneously recorded grid cells before and during hippocampal inactivation. Our analysis revealed evidence of <strong><span style=\"color: #ff0000;\">network coherence in grid cells even in\u00a0<\/span><\/strong><strong><span style=\"color: #ff0000;\">the absence of hippocampal input to the MEC, both in regular grid cells and in those that became\u00a0<\/span><\/strong><strong><span style=\"color: #ff0000;\">head-direction cells after hippocampal inactivation<\/span><\/strong>. This favors models, <strong><span style=\"color: #ff0000;\">which suggest that phase<\/span><\/strong><br \/>\n<strong><span style=\"color: #ff0000;\">relations between grid cells in the MEC are dependent on intrinsic connectivity within the MEC<\/span><\/strong>.&#8221;<\/p>\n<p>For further info, please read the paper Almog et al. 2019.\u00a0<\/p>\n<p>Noam Almog, Gilad Tocker, Tora Bonnevie, Edvard Moser, May-Britt Moser, Dori Derdikman. <a href=\"https:\/\/elifesciences.org\/articles\/47147\"><strong>During hippocampal inactivation, grid cells maintain their synchrony, even when the grid pattern is lost<\/strong><\/a>.\u00a0eLife 2019;8:e47147 DOI: 10.7554\/eLife.47147<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Noam Almog, Gilad Tocker, Tora Bonnevie, Edvard Moser, May-Britt Moser, Dori Derdikman. During hippocampal inactivation, grid cells maintain their synchrony, even when the grid pattern is lost.\u00a0eLife 2019;8:e47147 DOI: 10.7554\/eLife.47147 Abstract\u00a0&#8220;The grid cell network in the medial entorhinal cortex (MEC) has been subject to thorough testing and analysis, and many theories for their formation have [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[96,346],"tags":[103,396,104],"_links":{"self":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2043"}],"collection":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2043"}],"version-history":[{"count":1,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2043\/revisions"}],"predecessor-version":[{"id":2044,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2043\/revisions\/2044"}],"wp:attachment":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2043"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2043"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2043"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}