{"id":2056,"date":"2019-11-06T13:41:44","date_gmt":"2019-11-06T03:41:44","guid":{"rendered":"https:\/\/www.cognav.net\/?p=2056"},"modified":"2019-11-06T16:55:44","modified_gmt":"2019-11-06T06:55:44","slug":"how-abstract-and-discrete-relational-structures-are-represented-combined-and-navigated-in-the-human-brain","status":"publish","type":"post","link":"https:\/\/braininspirednavigation.com\/?p=2056","title":{"rendered":"How abstract and discrete relational structures are represented, combined, and navigated in the human brain?"},"content":{"rendered":"<p style=\"text-align: justify;\">Seongmin A. Park, Douglas S. Miller, Hamed Nili, Charan Ranganath, Erie D. Boorman. <a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/810051v1\"><strong>Map making: Constructing, combining, and navigating abstract cognitive maps<\/strong><\/a>.\u00a0bioRxiv 810051; doi: https:\/\/doi.org\/10.1101\/810051<\/p>\n<p style=\"text-align: justify;\">ABSTRACT<br \/>\n&#8220;<span style=\"color: #ff0000;\"><strong>Cognitive maps are thought to enable model-based inferences from limited experience that can guide novel decisions\u2013a hallmark of goal-directed behavior<\/strong><\/span>. We tested <span style=\"color: #ff0000;\"><strong>whether the hippocampus (HC), entorhinal cortex (EC), and ventromedial prefrontal cortex (vmPFC)\/medial orbitofrontal cortex (mOFC) organize abstract and discrete relational information into a cognitive map to guide novel choices<\/strong><\/span>. Subjects learned the status of people in two separate unseen 2-D social hierarchies defined by competence and popularity piecemeal from binary comparisons. Although only one dimension was ever behaviorally relevant, multivariate activity patterns in HC, EC and mOFC were linearly related to the Euclidian distance between people in the mentally reconstructed 2-D space. Hubs created unique comparisons between the two hierarchies, enabling inferences between novel pairs of people. We found that both behavior and neural activity in EC and vmPFC\/mOFC reflected the Euclidian distance to the retrieved hub, which was reinstated in HC. <strong><span style=\"color: #ff0000;\">These findings reveal how abstract and discrete relational structures are represented, combined, and navigated in the human brain<\/span><\/strong>.&#8221;<\/p>\n<p style=\"text-align: justify;\">Seongmin A. Park, Douglas S. Miller, Hamed Nili, Charan Ranganath, Erie D. Boorman. <a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/810051v1\"><strong>Map making: Constructing, combining, and navigating abstract cognitive maps<\/strong><\/a>.\u00a0bioRxiv 810051; doi: https:\/\/doi.org\/10.1101\/810051<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Seongmin A. Park, Douglas S. Miller, Hamed Nili, Charan Ranganath, Erie D. Boorman. Map making: Constructing, combining, and navigating abstract cognitive maps.\u00a0bioRxiv 810051; doi: https:\/\/doi.org\/10.1101\/810051 ABSTRACT &#8220;Cognitive maps are thought to enable model-based inferences from limited experience that can guide novel decisions\u2013a hallmark of goal-directed behavior. We tested whether the hippocampus (HC), entorhinal cortex (EC), [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[96,346,419,519],"tags":[561,562,349,365],"_links":{"self":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2056"}],"collection":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2056"}],"version-history":[{"count":1,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2056\/revisions"}],"predecessor-version":[{"id":2057,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2056\/revisions\/2057"}],"wp:attachment":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2056"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2056"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2056"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}