{"id":2075,"date":"2019-11-15T11:36:41","date_gmt":"2019-11-15T01:36:41","guid":{"rendered":"https:\/\/www.cognav.net\/?p=2075"},"modified":"2019-11-15T11:36:41","modified_gmt":"2019-11-15T01:36:41","slug":"how-the-spatial-tuning-relates-to-memory-for-events-involving-locations","status":"publish","type":"post","link":"https:\/\/braininspirednavigation.com\/?p=2075","title":{"rendered":"How the spatial tuning relates to memory for events involving locations?"},"content":{"rendered":"<p style=\"text-align: justify;\">Qasim, S.E., Miller, J., Inman, C.S. et al. <a href=\"https:\/\/www.nature.com\/articles\/s41593-019-0523-z\"><strong>Memory retrieval modulates spatial tuning of single neurons in the human entorhinal cortex<\/strong><\/a>. Nat Neurosci (2019) doi:10.1038\/s41593-019-0523-z<\/p>\n<p style=\"text-align: justify;\">Abstract<br \/>\n&#8220;T<strong><span style=\"color: #ff0000;\">he medial temporal lobe is critical for both spatial navigation and memory.<\/span><\/strong> Although <strong><span style=\"color: #ff0000;\">single neurons<\/span><\/strong> in the medial temporal lobe<strong><span style=\"color: #ff0000;\"> activate to represent locations in the environment during navigation<\/span><\/strong>, <strong><span style=\"color: #ff0000;\">how this spatial tuning relates to memory for events involving those locations remains unclear<\/span><\/strong>. We examined memory-related changes in spatial tuning by recording single-neuron activity from neurosurgical patients performing a virtual-reality object\u2013location memory task. <strong><span style=\"color: #ff0000;\">We identified \u2018memory-trace cells\u2019 with activity that was spatially tuned to the retrieved location of the specific object that participants were cued to remember.<\/span> <span style=\"color: #ff0000;\">Memory-trace cells<\/span> <\/strong>in the entorhinal cortex, in particular, <strong><span style=\"color: #ff0000;\">encoded discriminable representations of different memories through a memory-specific rate code<\/span><\/strong>. These findings indicate that single neurons in the human entorhinal cortex change their spatial tuning to target relevant memories for retrieval.&#8221;<\/p>\n<p style=\"text-align: justify;\">Qasim, S.E., Miller, J., Inman, C.S. et al. <a href=\"https:\/\/www.nature.com\/articles\/s41593-019-0523-z\"><strong>Memory retrieval modulates spatial tuning of single neurons in the human entorhinal cortex<\/strong><\/a>. Nat Neurosci (2019) doi:10.1038\/s41593-019-0523-z<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Qasim, S.E., Miller, J., Inman, C.S. et al. Memory retrieval modulates spatial tuning of single neurons in the human entorhinal cortex. Nat Neurosci (2019) doi:10.1038\/s41593-019-0523-z Abstract &#8220;The medial temporal lobe is critical for both spatial navigation and memory. Although single neurons in the medial temporal lobe activate to represent locations in the environment during navigation, [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[96,346,419,519],"tags":[578,576,575,577],"_links":{"self":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2075"}],"collection":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2075"}],"version-history":[{"count":1,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2075\/revisions"}],"predecessor-version":[{"id":2076,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2075\/revisions\/2076"}],"wp:attachment":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2075"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2075"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2075"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}