{"id":2148,"date":"2019-12-28T23:52:50","date_gmt":"2019-12-28T13:52:50","guid":{"rendered":"https:\/\/www.cognav.net\/?p=2148"},"modified":"2019-12-28T23:52:50","modified_gmt":"2019-12-28T13:52:50","slug":"how-does-the-primate-hippocampus-represent-objects-and-space-during-virtual-navigation","status":"publish","type":"post","link":"https:\/\/braininspirednavigation.com\/?p=2148","title":{"rendered":"How does the primate hippocampus represent objects and space during virtual navigation?"},"content":{"rendered":"<p style=\"text-align: justify;\">Gulli, Roberto A., Lyndon R. Duong, Benjamin W. Corrigan, Guillaume Doucet, Sylvain Williams, Stefano Fusi, and Julio C. Martinez-Trujillo. &#8220;<a href=\"https:\/\/www.nature.com\/articles\/s41593-019-0548-3\"><strong>Context-dependent representations of objects and space in the primate hippocampus during virtual navigation<\/strong><\/a>.&#8221; Nature Neuroscience 23, no. 1 (2020): 103-112.<\/p>\n<p style=\"text-align: justify;\">Abstract<br \/>\n&#8220;<span style=\"color: #ff0000;\"><strong>The hippocampus is implicated in associative memory and spatial navigatio<\/strong><\/span>n. To investigate <strong><span style=\"color: #ff0000;\">how these functions are mixed in the hippocampus<\/span><\/strong>, we recorded from single hippocampal neurons in macaque monkeys navigating a virtual maze during a foraging task and a context\u2013object associative memory task. During both tasks, single neurons encoded information about spatial position; a linear classifier also decoded position. However, the population code for space did not generalize across tasks, particularly where stimuli relevant to the associative memory task appeared. Single-neuron and population-level analyses revealed that cross-task changes were due to selectivity for nonspatial features of the associative memory task when they were visually available (perceptual coding) and following their disappearance (mnemonic coding). <strong><span style=\"color: #ff0000;\">Our results show that neurons in the primate hippocampus nonlinearly mix information about space and nonspatial elements of the environment in a task-dependent manner<\/span><\/strong>; <span style=\"color: #ff0000;\"><strong>this efficient code flexibly represents unique perceptual experiences and correspondent memories<\/strong><\/span>.&#8221;<\/p>\n<p style=\"text-align: justify;\">Gulli, Roberto A., Lyndon R. Duong, Benjamin W. Corrigan, Guillaume Doucet, Sylvain Williams, Stefano Fusi, and Julio C. Martinez-Trujillo. &#8220;<a href=\"https:\/\/www.nature.com\/articles\/s41593-019-0548-3\"><strong>Context-dependent representations of objects and space in the primate hippocampus during virtual navigation<\/strong><\/a>.&#8221; Nature Neuroscience 23, no. 1 (2020): 103-112.<\/p>\n<p>Data:\u00a0<a href=\"https:\/\/robertogulli.com\/data\/\">https:\/\/robertogulli.com\/data\/<\/a>\u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Gulli, Roberto A., Lyndon R. Duong, Benjamin W. Corrigan, Guillaume Doucet, Sylvain Williams, Stefano Fusi, and Julio C. Martinez-Trujillo. &#8220;Context-dependent representations of objects and space in the primate hippocampus during virtual navigation.&#8221; Nature Neuroscience 23, no. 1 (2020): 103-112. Abstract &#8220;The hippocampus is implicated in associative memory and spatial navigation. To investigate how these functions [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[96,636,419,519],"tags":[349,648,651,649,644,647,645,588,650,646],"_links":{"self":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2148"}],"collection":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2148"}],"version-history":[{"count":1,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2148\/revisions"}],"predecessor-version":[{"id":2149,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2148\/revisions\/2149"}],"wp:attachment":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2148"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2148"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2148"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}