{"id":2246,"date":"2020-02-16T11:28:32","date_gmt":"2020-02-16T01:28:32","guid":{"rendered":"https:\/\/www.cognav.net\/?p=2246"},"modified":"2020-02-16T11:39:43","modified_gmt":"2020-02-16T01:39:43","slug":"how-do-the-brain-circuits-work-in-encoding-retrieval-and-discrimination-of-episodic-memories","status":"publish","type":"post","link":"https:\/\/braininspirednavigation.com\/?p=2246","title":{"rendered":"How do the brain circuits work in encoding, retrieval and discrimination of episodic memories?"},"content":{"rendered":"<p style=\"text-align: justify;\">Hainmueller, T., Bartos, M. <a href=\"https:\/\/www.nature.com\/articles\/s41583-019-0260-z\"><strong>Dentate gyrus circuits for encoding, retrieval and discrimination of episodic memories<\/strong><\/a>. Nat Rev Neurosci (2020). https:\/\/doi.org\/10.1038\/s41583-019-0260-z<\/p>\n<p style=\"text-align: justify;\">Abstract<br \/>\n&#8220;<strong><span style=\"color: #ff0000;\">The dentate gyrus (DG) has a key role in hippocampal memory formation<\/span><\/strong>. Intriguingly, DG lesions impair many, but not all, hippocampus-dependent mnemonic functions, indicating that the rest of the hippocampus (CA1\u2013CA3) can operate autonomously under certain conditions. An extensive body of theoretical work has proposed <strong><span style=\"color: #ff0000;\">how the architectural elements and various cell types of the DG may underlie its function in cognition<\/span><\/strong>. Recent studies recorded and manipulated the activity of different neuron types in the DG during memory tasks and have provided exciting new insights into <strong><span style=\"color: #ff0000;\">the mechanisms of DG computational processes<\/span><\/strong>, particularly for <strong><span style=\"color: #ff0000;\">the encoding, retrieval and discrimination of similar memories<\/span><\/strong>. Here, we review these DG-dependent mnemonic functions in light of the new findings and explore mechanistic links between <strong><span style=\"color: #ff0000;\">t<\/span><span style=\"color: #ff0000;\">he cellular and network properties<\/span> <\/strong>of, and <strong><span style=\"color: #ff0000;\">the computations performed by, the DG<\/span><\/strong>.&#8221;<\/p>\n<p style=\"text-align: justify;\">Hainmueller, T., Bartos, M. <a href=\"https:\/\/www.nature.com\/articles\/s41583-019-0260-z\"><strong>Dentate gyrus circuits for encoding, retrieval and discrimination of episodic memories<\/strong><\/a>. Nat Rev Neurosci (2020). https:\/\/doi.org\/10.1038\/s41583-019-0260-z<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Hainmueller, T., Bartos, M. Dentate gyrus circuits for encoding, retrieval and discrimination of episodic memories. Nat Rev Neurosci (2020). https:\/\/doi.org\/10.1038\/s41583-019-0260-z Abstract &#8220;The dentate gyrus (DG) has a key role in hippocampal memory formation. Intriguingly, DG lesions impair many, but not all, hippocampus-dependent mnemonic functions, indicating that the rest of the hippocampus (CA1\u2013CA3) can operate autonomously [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[96,636,419,519],"tags":[776,725,775,718,520,576,777],"_links":{"self":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2246"}],"collection":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2246"}],"version-history":[{"count":1,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2246\/revisions"}],"predecessor-version":[{"id":2247,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2246\/revisions\/2247"}],"wp:attachment":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2246"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2246"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2246"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}