{"id":2273,"date":"2020-04-10T10:55:35","date_gmt":"2020-04-10T00:55:35","guid":{"rendered":"https:\/\/www.cognav.net\/?p=2273"},"modified":"2020-04-10T10:55:35","modified_gmt":"2020-04-10T00:55:35","slug":"how-is-speed-signal-utilized-by-the-brain-for-performing-path-integration","status":"publish","type":"post","link":"https:\/\/braininspirednavigation.com\/?p=2273","title":{"rendered":"How is speed signal utilized by the brain for performing path integration?"},"content":{"rendered":"<p style=\"text-align: justify;\">Holger Dannenberg, Hallie Lazaro, Pranav Nambiar, Alec Hoyland, Michael E Hasselmo. <a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2020.04.06.027466v1\"><strong>Effects of visual inputs on neural dynamics for coding of location and running speed in medial entorhinal cortex<\/strong><\/a>.\u00a0bioRxiv 2020.04.06.027466; doi: https:\/\/doi.org\/10.1101\/2020.04.06.027466<\/p>\n<p style=\"text-align: justify;\">Abstract<br \/>\n&#8220;Neuronal representations of spatial location and movement speed are important for a broad range of cognitive functions, including spatial self-localization and memory-guided navigation. <strong><span style=\"color: #ff0000;\">Two possible speed signals, by theta frequency or by firing rate, have been hypothesized to provide the velocity signal needed for generating the spatially periodic grid cell firing patter<\/span><span style=\"color: #ff0000;\">n<\/span><\/strong>. However, <strong><span style=\"color: #ff0000;\">which of these speed signals is utilized by the brain remains unknown<\/span><\/strong>. By manipulating visual inputs and analyzing the time-courses of evoked changes, <strong><span style=\"color: #ff0000;\">we demonstrate that changes in spatial stability of grid cell firing correlate in time with changes in speed coding by local field potential theta frequency<\/span><\/strong>. In contrast, <strong><span style=\"color: #ff0000;\">visual inputs do not affect speed coding by firing rate even if baseline firing rates are changed<\/span><\/strong>. Moreover, grid cells maintain a spatially periodic firing pattern, though less stable, in complete darkness. <strong><span style=\"color: #ff0000;\">These data suggest that mice use an oscillatory speed signal to perform path integration<\/span><\/strong>.&#8221;<\/p>\n<p style=\"text-align: justify;\">Holger Dannenberg, Hallie Lazaro, Pranav Nambiar, Alec Hoyland, Michael E Hasselmo. <a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2020.04.06.027466v1\"><strong>Effects of visual inputs on neural dynamics for coding of location and running speed in medial entorhinal cortex<\/strong><\/a>.\u00a0bioRxiv 2020.04.06.027466; doi: https:\/\/doi.org\/10.1101\/2020.04.06.027466<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Holger Dannenberg, Hallie Lazaro, Pranav Nambiar, Alec Hoyland, Michael E Hasselmo. Effects of visual inputs on neural dynamics for coding of location and running speed in medial entorhinal cortex.\u00a0bioRxiv 2020.04.06.027466; doi: https:\/\/doi.org\/10.1101\/2020.04.06.027466 Abstract &#8220;Neuronal representations of spatial location and movement speed are important for a broad range of cognitive functions, including spatial self-localization and memory-guided [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[96],"tags":[367,799,292,798,800],"_links":{"self":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2273"}],"collection":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2273"}],"version-history":[{"count":1,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2273\/revisions"}],"predecessor-version":[{"id":2274,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2273\/revisions\/2274"}],"wp:attachment":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2273"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2273"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2273"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}