{"id":2319,"date":"2020-08-22T11:09:27","date_gmt":"2020-08-22T01:09:27","guid":{"rendered":"https:\/\/www.cognav.net\/?p=2319"},"modified":"2020-08-22T11:09:27","modified_gmt":"2020-08-22T01:09:27","slug":"how-do-rodents-execute-efficient-multi-step-routes-to-goals-in-novel-environments","status":"publish","type":"post","link":"https:\/\/braininspirednavigation.com\/?p=2319","title":{"rendered":"How do rodents execute efficient multi-step routes to goals in novel environments?"},"content":{"rendered":"<p style=\"text-align: justify;\">Philip Shamash, Sarah F. Olesen, Panagiota Iordanidou, Dario Campagner, Banerjee Nabhojit, Tiago Branco. <a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2020.08.19.256867v1\"><strong>Mice learn multi-step routes by memorizing subgoal locations<\/strong><\/a>. bioRxiv 2020.08.19.256867; doi: https:\/\/doi.org\/10.1101\/2020.08.19.256867<\/p>\n<p style=\"text-align: justify;\">Abstract<br \/>\n&#8220;<span style=\"color: #ff0000;\"><strong>Animals must rapidly gather spatial information about new environments so that they can quickly reach food or safety even when direct paths are unavailable<\/strong><\/span>. <strong><span style=\"color: #ff0000;\">The behavioral strategies used to implement multi-step routes to goals in naturalistic settings are unknown<\/span><\/strong>. Here we show that mice spontaneously learn a subgoal memory strategy while escaping to shelter or seeking food in an obstructed environment. <strong><span style=\"color: #ff0000;\">We first investigated how mice navigate to shelter in response to threats when the direct path is blocked by a wall<\/span><\/strong>. Initially, mice ran straight toward the shelter and circumvented the obstacle using sensory cues. Over the course of 20 minutes, however, they switched to a spatial memory strategy to execute spatially efficient paths. Efficient escape routes were not learned by reinforcing egocentric actions or by constructing an unbiased internal map during exploration. Instead, <strong><span style=\"color: #ff0000;\">mice used a hybrid strategy: they memorized specific subgoal locations encountered during previous running movements toward the obstacle<\/span><\/strong>. We then found that the same behavioral strategy is also used in a reward-seeking task. These results show that <strong><span style=\"color: #ff0000;\">spontaneous memorization of local subgoals is a fundamental strategy by which rodents execute efficient multi-step routes to goals in novel environments<\/span><\/strong>.&#8221;<\/p>\n<p style=\"text-align: justify;\">Philip Shamash, Sarah F. Olesen, Panagiota Iordanidou, Dario Campagner, Banerjee Nabhojit, Tiago Branco. <a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2020.08.19.256867v1\"><strong>Mice learn multi-step routes by memorizing subgoal locations<\/strong><\/a>. bioRxiv 2020.08.19.256867; doi: https:\/\/doi.org\/10.1101\/2020.08.19.256867<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Philip Shamash, Sarah F. Olesen, Panagiota Iordanidou, Dario Campagner, Banerjee Nabhojit, Tiago Branco. Mice learn multi-step routes by memorizing subgoal locations. bioRxiv 2020.08.19.256867; doi: https:\/\/doi.org\/10.1101\/2020.08.19.256867 Abstract &#8220;Animals must rapidly gather spatial information about new environments so that they can quickly reach food or safety even when direct paths are unavailable. The behavioral strategies used to [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[96,419,519],"tags":[315,148,825,826],"_links":{"self":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2319"}],"collection":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2319"}],"version-history":[{"count":1,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2319\/revisions"}],"predecessor-version":[{"id":2320,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2319\/revisions\/2320"}],"wp:attachment":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2319"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2319"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2319"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}