{"id":2331,"date":"2020-08-26T19:32:57","date_gmt":"2020-08-26T09:32:57","guid":{"rendered":"https:\/\/www.cognav.net\/?p=2331"},"modified":"2020-08-26T19:32:57","modified_gmt":"2020-08-26T09:32:57","slug":"how-does-the-retrosplenial-cortex-perform-1d-path-integration-and-represent-spatial-context","status":"publish","type":"post","link":"https:\/\/braininspirednavigation.com\/?p=2331","title":{"rendered":"How does the retrosplenial cortex perform 1D path integration and represent spatial context?"},"content":{"rendered":"<p style=\"text-align: justify;\">Ju M, Gaussier P. <a href=\"https:\/\/link.springer.com\/article\/10.1007\/s00422-020-00833-x\"><strong>A model of path integration and representation of spatial context in the retrosplenial cortex<\/strong><\/a>. Biological Cybernetics. 2020 Apr;114(2):303-313. DOI: 10.1007\/s00422-020-00833-x.<\/p>\n<p style=\"text-align: justify;\">Abstract <br \/>\n&#8220;Inspired by recent biological experiments, <strong><span style=\"color: #ff0000;\">we simulate animals moving in different environments (open space, spiral mazes and on a treadmill) to test the performances of a simple model of the retrosplenial cortex (RSC) acting as a path integration (PI) and as a categorization mechanism.<\/span><\/strong> The connection between the hippocampus, RSC and the entorhinal cortex is revealed through a novel perspective. <strong><span style=\"color: #ff0000;\">We suppose that the path integration is performed by the information coming from RSC<\/span><\/strong>. <strong><span style=\"color: #ff0000;\">Grid cells in the entorhinal cortex then can be built as the result of a modulo projection of RSC activity<\/span><\/strong>. In our model, PI is performed by a 1D field of neurons acting as a simple low-pass filter of head direction (HD) cells modulated by the linear velocity of the animal. Our paper focuses on the constraints on the HD cells shape for a good approximation of PI. Recording of neurons on our 1D PI field shows these neurons would not be intuitively interpreted as performing PI. Using inputs coming from a narrow neighbouring projection of our PI field creates place cell-like activities in the RSC when the mouse runs on the treadmill. <strong><span style=\"color: #ff0000;\">This can be the result of local self-organizing maps representing blobs of neurons in the RSC (e.g. cortical columns)<\/span><\/strong>. <strong><span style=\"color: #ff0000;\">Other simulations show that accessing the whole PI field would induce place cells whatever the environment is<\/span><\/strong>. Since this property is not observed, we conclude that the categorization neurons in the RSC should have access to only a small fraction of the PI field.&#8221;<\/p>\n<p style=\"text-align: justify;\">Ju M, Gaussier P. <a href=\"https:\/\/link.springer.com\/article\/10.1007\/s00422-020-00833-x\"><strong>A model of path integration and representation of spatial context in the retrosplenial cortex<\/strong><\/a>. Biological Cybernetics. 2020 Apr;114(2):303-313. DOI: 10.1007\/s00422-020-00833-x.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Ju M, Gaussier P. A model of path integration and representation of spatial context in the retrosplenial cortex. Biological Cybernetics. 2020 Apr;114(2):303-313. DOI: 10.1007\/s00422-020-00833-x. Abstract &#8220;Inspired by recent biological experiments, we simulate animals moving in different environments (open space, spiral mazes and on a treadmill) to test the performances of a simple model of the [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[96],"tags":[292],"_links":{"self":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2331"}],"collection":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2331"}],"version-history":[{"count":1,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2331\/revisions"}],"predecessor-version":[{"id":2332,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2331\/revisions\/2332"}],"wp:attachment":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2331"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2331"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2331"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}