{"id":2399,"date":"2021-01-29T18:38:37","date_gmt":"2021-01-29T08:38:37","guid":{"rendered":"https:\/\/www.cognav.net\/?p=2399"},"modified":"2021-01-29T18:38:37","modified_gmt":"2021-01-29T08:38:37","slug":"whether-and-how-the-3d-position-and-velocity-of-the-head-and-eyes-are-represented-in-the-rodent-mec-neural-circuitry-supporting-navigation","status":"publish","type":"post","link":"https:\/\/braininspirednavigation.com\/?p=2399","title":{"rendered":"Whether and how the 3D position and velocity of the head and eyes are represented in the rodent MEC neural circuitry supporting navigation?"},"content":{"rendered":"<p style=\"text-align: justify;\">Caitlin S. Mallory, Kiah Hardcastle, Malcolm G. Campbell, Alexander Attinger, Isabel I. C. Low, Jennifer L. Raymond &amp; Lisa M. Giocomo.\u00a0<a href=\"https:\/\/www.nature.com\/articles\/s41467-021-20936-8\"><strong>Mouse entorhinal cortex encodes a diverse repertoire of self-motion signals<\/strong><\/a>.\u00a0Nat Commun\u00a0<b>12,\u00a0<\/b>671 (2021). https:\/\/doi.org\/10.1038\/s41467-021-20936-8<\/p>\n<p style=\"text-align: justify;\">Abstract<br \/>\n&#8220;Neural circuits generate representations of the external world from multiple information streams. The navigation system provides an exceptional lens through which we may gain insights about how such computations are implemented. <span style=\"color: #ff0000;\"><strong>Neural circuits in the medial temporal lobe construct a map-like representation of space that supports navigation<\/strong><\/span>. <span style=\"color: #ff0000;\"><strong>This computation integrates multiple sensory cues, and, in addition, is thought to require cues related to the individual\u2019s movement through the environment.<\/strong><\/span> Here, <span style=\"color: #ff0000;\"><strong>we identify multiple self-motion signals, related to the position and velocity of the head and eyes, encoded by neurons in a key node of the navigation circuitry of mice, the medial entorhinal cortex (MEC)<\/strong><\/span>. The representation of these signals is highly integrated with other cues in individual neurons. <strong><span style=\"color: #ff0000;\">S<\/span><span style=\"color: #ff0000;\">uch information could be used to compute the allocentric location of landmarks from visual cues and to generate internal representations of space<\/span><\/strong>.&#8221;<\/p>\n<p style=\"text-align: justify;\">Caitlin S. Mallory, Kiah Hardcastle, Malcolm G. Campbell, Alexander Attinger, Isabel I. C. Low, Jennifer L. Raymond &amp; Lisa M. Giocomo.\u00a0<a href=\"https:\/\/www.nature.com\/articles\/s41467-021-20936-8\"><strong>Mouse entorhinal cortex encodes a diverse repertoire of self-motion signals<\/strong><\/a>.\u00a0Nat Commun\u00a0<b>12,\u00a0<\/b>671 (2021). https:\/\/doi.org\/10.1038\/s41467-021-20936-8<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Caitlin S. Mallory, Kiah Hardcastle, Malcolm G. Campbell, Alexander Attinger, Isabel I. C. Low, Jennifer L. Raymond &amp; Lisa M. Giocomo.\u00a0Mouse entorhinal cortex encodes a diverse repertoire of self-motion signals.\u00a0Nat Commun\u00a012,\u00a0671 (2021). https:\/\/doi.org\/10.1038\/s41467-021-20936-8 Abstract &#8220;Neural circuits generate representations of the external world from multiple information streams. The navigation system provides an exceptional lens through which [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[819,390,96],"tags":[889,888,890,729,175,511,887,512],"_links":{"self":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2399"}],"collection":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2399"}],"version-history":[{"count":1,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2399\/revisions"}],"predecessor-version":[{"id":2400,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2399\/revisions\/2400"}],"wp:attachment":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2399"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2399"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2399"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}