{"id":2448,"date":"2021-07-09T10:26:34","date_gmt":"2021-07-09T00:26:34","guid":{"rendered":"https:\/\/www.cognav.net\/?p=2448"},"modified":"2021-07-09T10:26:34","modified_gmt":"2021-07-09T00:26:34","slug":"how-does-the-hippocampus-represent-3d-space-in-past-present-and-future","status":"publish","type":"post","link":"https:\/\/braininspirednavigation.com\/?p=2448","title":{"rendered":"How does the hippocampus represent 3D space in past, present and future?"},"content":{"rendered":"<p style=\"text-align: justify;\">Nicholas M. Dotson and Michael M. Yartsev. <a href=\"https:\/\/science.sciencemag.org\/content\/373\/6551\/242\"><strong>Nonlocal spatiotemporal representation in the hippocampus of freely flying bats<\/strong><\/a>. SCIENCE 09 JUL 2021 : 242-247<\/p>\n<p style=\"text-align: justify;\">&#8220;The neural code for 3D map\u2013based navigation in area CA1 of bats forms a continuum through space and time.&#8221;<\/p>\n<p style=\"text-align: justify;\"><strong>Representing space in past and future<\/strong><br \/>\n&#8220;As an organism moves through space,<strong><span style=\"color: #ff0000;\"> its brain has to remember its most recent location and anticipate its future position, not just its current place in the world<\/span><\/strong>. Earlier studies reported so-called retrospective and prospective place coding in rats while they were running along linear tracks. However,<strong><span style=\"color: #ff0000;\"> it would be advantageous to study an animal that rapidly moves through three-dimensional space with high precision<\/span><\/strong>. Dotson and Yartsev recorded from flying bats to investigate <strong><span style=\"color: #ff0000;\">whether place cell activity in hippocampus area CA1 represents local (current) or nonlocal positions<\/span><\/strong>. They discovered that <strong><span style=\"color: #ff0000;\">the hippocampus not only encodes the bat&#8217;s present location but also signals its positions in the past and future<\/span><\/strong>.&#8221;<\/p>\n<p style=\"text-align: justify;\"><strong>Abstract<\/strong><br \/>\n&#8220;<strong><span style=\"color: #ff0000;\">Navigation occurs through a continuum of space and time<\/span><\/strong>. The hippocampus is known to encode the immediate position of moving animals. However, <strong><span style=\"color: #ff0000;\">active navigation, especially at high speeds, may require representing navigational information beyond the present moment<\/span><\/strong>. Using wireless electrophysiological recordings in freely flying bats, <strong><span style=\"color: #ff0000;\">we demonstrate that neural activity in area CA1 predominantly encodes nonlocal spatial information up to meters away from the bat\u2019s present position<\/span><\/strong>. <strong><span style=\"color: #ff0000;\">This spatiotemporal representation extends both forward and backward in time, with an emphasis on future locations, and is found during both random exploration and goal-directed navigation<\/span><\/strong>. The representation of position thus extends along a continuum, with each moment <strong><span style=\"color: #ff0000;\">containing information about past, present, and future<\/span><\/strong>, and may <strong><span style=\"color: #ff0000;\">provide a key mechanism for navigating along self-selected and remembered paths<\/span><\/strong>.&#8221;<\/p>\n<p style=\"text-align: justify;\">Nicholas M. Dotson and Michael M. Yartsev. <a href=\"https:\/\/science.sciencemag.org\/content\/373\/6551\/242\"><strong>Nonlocal spatiotemporal representation in the hippocampus of freely flying bats<\/strong><\/a>. SCIENCE 09 JUL 2021 : 242-247<\/p>\n<p style=\"text-align: justify;\">\u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Nicholas M. Dotson and Michael M. Yartsev. Nonlocal spatiotemporal representation in the hippocampus of freely flying bats. SCIENCE 09 JUL 2021 : 242-247 &#8220;The neural code for 3D map\u2013based navigation in area CA1 of bats forms a continuum through space and time.&#8221; Representing space in past and future &#8220;As an organism moves through space, its [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[390,389,96,346],"tags":[863,349,915,916],"_links":{"self":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2448"}],"collection":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2448"}],"version-history":[{"count":1,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2448\/revisions"}],"predecessor-version":[{"id":2449,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2448\/revisions\/2449"}],"wp:attachment":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2448"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2448"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2448"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}