{"id":2451,"date":"2021-07-15T10:58:51","date_gmt":"2021-07-15T00:58:51","guid":{"rendered":"https:\/\/www.cognav.net\/?p=2451"},"modified":"2021-07-15T10:58:51","modified_gmt":"2021-07-15T00:58:51","slug":"how-does-the-human-brain-encode-egocentric-spatial-maps","status":"publish","type":"post","link":"https:\/\/braininspirednavigation.com\/?p=2451","title":{"rendered":"How does the human brain encode egocentric spatial maps?"},"content":{"rendered":"<p style=\"text-align: justify;\">Lukas Kunz, Armin Brandt, Peter C. Reinacher, Bernhard P. Staresina, Eric T. Reifenstein, Christoph T. Weidemann, Nora A. Herweg, Ansh Patel, Melina Tsitsiklis, Richard Kempter, Michael J. Kahana, Andreas Schulze-Bonhage, Joshua Jacobs. <a href=\"https:\/\/www.cell.com\/neuron\/fulltext\/S0896-6273(21)00460-8\"><strong>A neural code for egocentric spatial maps in the human medial temporal lobe<\/strong><\/a>. Neuron, 2021.\u00a0https:\/\/doi.org\/10.1016\/j.neuron.2021.06.019\u00a0<\/p>\n<p style=\"text-align: justify;\"><strong>Highlights<\/strong><br \/>\n\u2022 Human single-neuron recordings during navigation identify egocentric bearing cells (EBCs)<br \/>\n\u2022 These EBCs provide a counterpart to allocentric, world-referenced spatial cell types<br \/>\n\u2022 EBCs encode self-centered bearings and distances toward reference points in space<br \/>\n\u2022 EBCs play a role in human spatial and episodic memory<br \/>\n<strong>Summary<\/strong><br \/>\n&#8220;<strong><span style=\"color: #ff0000;\">Spatial navigation and memory rely on neural systems that encode places, distances, and directions in relation to the external world or relative to the navigating organism<\/span><\/strong>. <strong><span style=\"color: #ff0000;\">Place, grid, and head-direction cells form key units of world-referenced, allocentric cognitive maps, but the neural basis of self-centered, egocentric representations remains poorly understood<\/span><\/strong>. Here, we used human single-neuron recordings during virtual spatial navigation tasks <strong><span style=\"color: #ff0000;\">to identify neurons providing a neural code for egocentric spatial maps in the human brain<\/span><\/strong>. Consistent with previous observations in rodents, <strong><span style=\"color: #ff0000;\">these neurons represented egocentric bearings toward reference points positioned throughout the environment<\/span><\/strong>. <strong><span style=\"color: #ff0000;\">Egocentric bearing cells were abundant in the parahippocampal cortex and supported vectorial representations of egocentric space by also encoding distances toward reference points<\/span><\/strong>. Beyond navigation, the observed neurons showed activity increases during spatial and episodic memory recall, suggesting that <strong><span style=\"color: #ff0000;\">egocentric bearing cells are not only relevant for navigation but also play a role in human memory<\/span><\/strong>.&#8221;<\/p>\n<p style=\"text-align: justify;\">Lukas Kunz, Armin Brandt, Peter C. Reinacher, Bernhard P. Staresina, Eric T. Reifenstein, Christoph T. Weidemann, Nora A. Herweg, Ansh Patel, Melina Tsitsiklis, Richard Kempter, Michael J. Kahana, Andreas Schulze-Bonhage, Joshua Jacobs. <a href=\"https:\/\/www.cell.com\/neuron\/fulltext\/S0896-6273(21)00460-8\"><strong>A neural code for egocentric spatial maps in the human medial temporal lobe<\/strong><\/a>. Neuron, 2021.\u00a0https:\/\/doi.org\/10.1016\/j.neuron.2021.06.019\u00a0<\/p>\n<p style=\"text-align: justify;\">\u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Lukas Kunz, Armin Brandt, Peter C. Reinacher, Bernhard P. Staresina, Eric T. Reifenstein, Christoph T. Weidemann, Nora A. Herweg, Ansh Patel, Melina Tsitsiklis, Richard Kempter, Michael J. Kahana, Andreas Schulze-Bonhage, Joshua Jacobs. A neural code for egocentric spatial maps in the human medial temporal lobe. Neuron, 2021.\u00a0https:\/\/doi.org\/10.1016\/j.neuron.2021.06.019\u00a0 Highlights \u2022 Human single-neuron recordings during navigation identify [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[96,346,419,532,519],"tags":[589,918,917],"_links":{"self":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2451"}],"collection":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2451"}],"version-history":[{"count":1,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2451\/revisions"}],"predecessor-version":[{"id":2452,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2451\/revisions\/2452"}],"wp:attachment":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2451"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2451"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2451"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}