{"id":2478,"date":"2021-10-12T17:05:08","date_gmt":"2021-10-12T07:05:08","guid":{"rendered":"https:\/\/www.cognav.net\/?p=2478"},"modified":"2021-10-12T17:05:08","modified_gmt":"2021-10-12T07:05:08","slug":"how-hippocampal-ensembles-combine-multimodal-sensory-cues","status":"publish","type":"post","link":"https:\/\/braininspirednavigation.com\/?p=2478","title":{"rendered":"How hippocampal ensembles combine multimodal sensory cues?"},"content":{"rendered":"<p style=\"text-align: justify;\">Dustin Fetterhoff, Andrey Sobolev, Christian Leibold. <a href=\"https:\/\/doi.org\/10.1016\/j.celrep.2021.109661\"><strong>Graded remapping of hippocampal ensembles under sensory conflicts<\/strong><\/a>. Cell Reports, Volume 36, Issue 11,\u00a02021.<\/p>\n<p style=\"text-align: justify;\">Summary<br \/>\n&#8220;<strong><span style=\"color: #ff0000;\">Hippocampal place cells are thought to constitute a cognitive map of space derived from multimodal sensory inputs<\/span><\/strong>. Alteration of allocentric (visual) cues in a fixed environment is known to induce modulations of place cell activity to varying degrees from rate changes to global remapping. <span style=\"color: #ff0000;\">To determine how hippocampal ensembles combine multimodal sensory cues, we examine hippocampal CA1 remapping in Mongolian gerbils in a 1D virtual reality experiment, during which self-motion cues (locomotor, vestibular, and optic flow information) and allocentric visual cues are altered<\/span>. We observe that self-motion cues are over-represented, but responsiveness to allocentric visual cues, although task-irrelevant, elicits both rate and global remapping in the hippocampal ensemble. <strong><span style=\"color: #ff0000;\">We propose that remapping can be reconciled by considering global, partial, and rate remapping on a continuous scale on which the graded change of activity in the entire CA1 population can be interpreted as the expectancy about the animal\u2019s spatial environment<\/span><\/strong>.&#8221;<\/p>\n<p style=\"text-align: justify;\">Dustin Fetterhoff, Andrey Sobolev, Christian Leibold. <a href=\"https:\/\/doi.org\/10.1016\/j.celrep.2021.109661\"><strong>Graded remapping of hippocampal ensembles under sensory conflicts<\/strong><\/a>. Cell Reports, Volume 36, Issue 11,\u00a02021.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Dustin Fetterhoff, Andrey Sobolev, Christian Leibold. Graded remapping of hippocampal ensembles under sensory conflicts. Cell Reports, Volume 36, Issue 11,\u00a02021. Summary &#8220;Hippocampal place cells are thought to constitute a cognitive map of space derived from multimodal sensory inputs. Alteration of allocentric (visual) cues in a fixed environment is known to induce modulations of place cell [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[114,96],"tags":[927,830],"_links":{"self":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2478"}],"collection":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2478"}],"version-history":[{"count":1,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2478\/revisions"}],"predecessor-version":[{"id":2479,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2478\/revisions\/2479"}],"wp:attachment":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2478"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2478"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2478"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}