{"id":2523,"date":"2022-01-05T12:34:59","date_gmt":"2022-01-05T02:34:59","guid":{"rendered":"https:\/\/www.cognav.net\/?p=2523"},"modified":"2022-01-05T12:38:49","modified_gmt":"2022-01-05T02:38:49","slug":"how-are-neural-representations-of-space-used-in-the-service-of-both-real-world-navigation-and-internal-mnemonic-processes","status":"publish","type":"post","link":"https:\/\/braininspirednavigation.com\/?p=2523","title":{"rendered":"How are neural representations of space used in the service of both real-world navigation and internal mnemonic processes?"},"content":{"rendered":"<p style=\"text-align: justify;\">Wenbo Tang and Shantanu P. Jadhav<span style=\"font-size: 13.3333px;\">.\u00a0<\/span><a href=\"https:\/\/www.annualreviews.org\/doi\/abs\/10.1146\/annurev-neuro-111020-084824\"><strong>Multiple-Timescale Representations of Space: Linking Memory to Navigation<\/strong><\/a>.\u00a0Annual Review of Neuroscience. Vol. 45:- (Volume publication date July 2022). Review in Advance first posted online on December 22, 2021. (Changes may still occur before final publication.) https:\/\/doi.org\/10.1146\/annurev-neuro-111020-084824<\/p>\n<p style=\"text-align: justify;\">Abstract<br \/>\n&#8220;When navigating through space, we must maintain a representation of our position in real time; when recalling a past episode, a memory can come back in a flash. Interestingly, the brain&#8217;s spatial representation system, including the hippocampus, supports these two distinct timescale functions. <strong><span style=\"color: #ff0000;\">How are neural representations of space used in the service of both real-world navigation and internal mnemonic processes?<\/span><\/strong> Recent progress has identified sequences of hippocampal place cells, evolving at multiple timescales in accordance with either navigational behaviors or internal oscillations, that underlie these functions. We review experimental findings on experience-dependent modulation of these sequential representations and consider <strong><span style=\"color: #ff0000;\">how they link real-world navigation to time-compressed memories<\/span><\/strong>. We further discuss recent work suggesting the prevalence of these sequences beyond hippocampus and propose that <strong><span style=\"color: #ff0000;\">these multiple-timescale mechanisms may represent a general algorithm for organizing cell assemblies<\/span><\/strong>, potentially <strong><span style=\"color: #ff0000;\">unifying the dual roles of the spatial representation system in memory and navigation<\/span><\/strong>.&#8221;<\/p>\n<p style=\"text-align: justify;\">Wenbo Tang and Shantanu P. Jadhav<span style=\"font-size: 13.3333px;\">.\u00a0<\/span><a href=\"https:\/\/www.annualreviews.org\/doi\/abs\/10.1146\/annurev-neuro-111020-084824\"><strong>Multiple-Timescale Representations of Space: Linking Memory to Navigation<\/strong><\/a>.\u00a0Annual Review of Neuroscience. Vol. 45:- (Volume publication date July 2022). Review in Advance first posted online on December 22, 2021. (Changes may still occur before final publication.) https:\/\/doi.org\/10.1146\/annurev-neuro-111020-084824<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Wenbo Tang and Shantanu P. Jadhav.\u00a0Multiple-Timescale Representations of Space: Linking Memory to Navigation.\u00a0Annual Review of Neuroscience. Vol. 45:- (Volume publication date July 2022). Review in Advance first posted online on December 22, 2021. (Changes may still occur before final publication.) https:\/\/doi.org\/10.1146\/annurev-neuro-111020-084824 Abstract &#8220;When navigating through space, we must maintain a representation of our position in [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[96,636,346,519],"tags":[148,950,85,243,588],"_links":{"self":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2523"}],"collection":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2523"}],"version-history":[{"count":1,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2523\/revisions"}],"predecessor-version":[{"id":2524,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2523\/revisions\/2524"}],"wp:attachment":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2523"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2523"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2523"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}