{"id":2557,"date":"2022-02-10T12:24:24","date_gmt":"2022-02-10T02:24:24","guid":{"rendered":"https:\/\/www.cognav.net\/?p=2557"},"modified":"2022-02-10T12:24:24","modified_gmt":"2022-02-10T02:24:24","slug":"whether-place-cells-encode-the-angular-and-linear-position-as-well-as-motion-direction-of-a-simple-stimulus-regardless-of-self-motion-memory-or-reward","status":"publish","type":"post","link":"https:\/\/braininspirednavigation.com\/?p=2557","title":{"rendered":"Whether place cells encode the angular and linear position as well as motion direction of a simple stimulus, regardless of self-motion, memory or reward?"},"content":{"rendered":"<p style=\"text-align: justify;\">Chinmay S. Purandare, Shonali Dhingra, Rodrigo Rios, Cliff Vuong, Thuc To, Ayaka Hachisuka, Krishna Choudhary &amp; Mayank R. Mehta. <a href=\"https:\/\/www.nature.com\/articles\/s41586-022-04404-x\"><strong>Moving bar of light evokes vectorial spatial selectivity in the immobile rat hippocampus<\/strong><\/a>. Nature (2022). https:\/\/doi.org\/10.1038\/s41586-022-04404-x<\/p>\n<p style=\"text-align: justify;\">Abstract<br \/>\n&#8220;Visual cortical neurons encode the position and motion direction of specific stimuli retrospectively, without any locomotion or task demand1. The hippocampus, which is a part of the visual system, is hypothesized to require self-motion or a cognitive task to generate allocentric spatial selectivity that is scalar, abstract2,3 and prospective4,5,6,7. <strong><span style=\"color: #ff0000;\">Here we measured rodent hippocampal selectivity to a moving bar of light in a body-fixed rat to bridge these seeming disparities.<\/span><\/strong> About 70% of dorsal CA1 neurons showed stable activity modulation as a function of the angular position of the bar, independent of behaviour and rewards. One-third of tuned cells also encoded the direction of revolution. In other experiments, neurons encoded the distance of the bar, with preference for approaching motion. <strong><span style=\"color: #ff0000;\">Collectively, these demonstrate visually evoked vectorial selectivity (VEVS). Unlike place cells, VEVS was retrospective.<\/span><\/strong> Changes in the visual stimulus or its predictability did not cause remapping but only caused gradual changes.<strong><span style=\"color: #ff0000;\"> Most VEVS-tuned neurons behaved like place cells during spatial exploration and the two selectivities were correlated.<\/span><\/strong> Thus, VEVS could form the basic building block of hippocampal activity. <strong><span style=\"color: #ff0000;\">When combined with self-motion, reward or multisensory stimuli8, it can generate the complexity of prospective representations including allocentric space9, time10,11 and episodes12<\/span><\/strong>.&#8221;<\/p>\n<p style=\"text-align: justify;\">Chinmay S. Purandare, Shonali Dhingra, Rodrigo Rios, Cliff Vuong, Thuc To, Ayaka Hachisuka, Krishna Choudhary &amp; Mayank R. Mehta. <a href=\"https:\/\/www.nature.com\/articles\/s41586-022-04404-x\"><strong>Moving bar of light evokes vectorial spatial selectivity in the immobile rat hippocampus<\/strong><\/a>. Nature (2022). https:\/\/doi.org\/10.1038\/s41586-022-04404-x<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Chinmay S. Purandare, Shonali Dhingra, Rodrigo Rios, Cliff Vuong, Thuc To, Ayaka Hachisuka, Krishna Choudhary &amp; Mayank R. Mehta. Moving bar of light evokes vectorial spatial selectivity in the immobile rat hippocampus. Nature (2022). https:\/\/doi.org\/10.1038\/s41586-022-04404-x Abstract &#8220;Visual cortical neurons encode the position and motion direction of specific stimuli retrospectively, without any locomotion or task demand1. [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[96,346],"tags":[978,979,349,977,870,511,205,976],"_links":{"self":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2557"}],"collection":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2557"}],"version-history":[{"count":1,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2557\/revisions"}],"predecessor-version":[{"id":2558,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2557\/revisions\/2558"}],"wp:attachment":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2557"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2557"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2557"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}