{"id":2578,"date":"2022-03-12T12:16:46","date_gmt":"2022-03-12T02:16:46","guid":{"rendered":"https:\/\/www.cognav.net\/?p=2578"},"modified":"2022-03-12T12:16:46","modified_gmt":"2022-03-12T02:16:46","slug":"how-do-hippocampal-neurons-contribute-to-memorizing-and-utilizing-information-acquired-through-social-observations-and-interactions","status":"publish","type":"post","link":"https:\/\/braininspirednavigation.com\/?p=2578","title":{"rendered":"How do hippocampal neurons contribute to memorizing and utilizing information acquired through social observations and interactions?"},"content":{"rendered":"<p style=\"text-align: justify;\">Mou, Xiang, Abhishekh Pokhrel, Prakul Suresh, and Daoyun Ji. &#8220;<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0896627321010138\"><strong>Observational learning promotes hippocampal remote awake replay toward future reward locations<\/strong><\/a>.&#8221; Neuron, Volume 110, Issue 5, 2 March 2022, Pages 891-902.e7<\/p>\n<p style=\"text-align: justify;\">Summary<br \/>\n&#8220;<strong><span style=\"color: #ff0000;\">The neural circuit mechanisms underlying observational learning, learning through observing the behavior of others, are poorly understood.<\/span><\/strong> Hippocampal place cells are important for spatial learning, and awake replay of place cell patterns is involved in spatial decisions. <strong><span style=\"color: #ff0000;\">Here we show that, in observer rats learning to run a maze by watching a demonstrator\u2019s spatial trajectories from a separate nearby observation box, place cell patterns during self-running in the maze are replayed remotely in the box.<\/span><\/strong> The contents of the remote awake replay preferentially target the maze\u2019s reward sites from both forward and reverse replay directions and reflect the observer\u2019s future correct trajectories in the maze. In contrast, under control conditions without a demonstrator, the remote replay is significantly reduced, and the preferences for reward sites and future trajectories disappear. <strong><span style=\"color: #ff0000;\">Our results suggest that social observation directs the contents of remote awake replay to guide spatial decisions in observational learning.<\/span><\/strong>&#8220;<\/p>\n<p style=\"text-align: justify;\">Mou, Xiang, Abhishekh Pokhrel, Prakul Suresh, and Daoyun Ji. &#8220;<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0896627321010138\"><strong>Observational learning promotes hippocampal remote awake replay toward future reward locations<\/strong><\/a>.&#8221; Neuron, Volume 110, Issue 5, 2 March 2022, Pages 891-902.e7<\/p>\n<p style=\"text-align: justify;\">\u00a0<\/p>\n<p style=\"text-align: justify;\">Further info:<\/p>\n<p style=\"text-align: justify;\">Fujisawa, Shigeyoshi, and Ayako Ouchi. &#8220;<a href=\"https:\/\/www.cell.com\/neuron\/fulltext\/S0896-6273(22)00132-5\">Replays of socially acquired information in the hippocampus<\/a>.&#8221;\u00a0<i>Neuron<\/i>\u00a0110, no. 5 (2022): 744-745.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Mou, Xiang, Abhishekh Pokhrel, Prakul Suresh, and Daoyun Ji. &#8220;Observational learning promotes hippocampal remote awake replay toward future reward locations.&#8221; Neuron, Volume 110, Issue 5, 2 March 2022, Pages 891-902.e7 Summary &#8220;The neural circuit mechanisms underlying observational learning, learning through observing the behavior of others, are poorly understood. Hippocampal place cells are important for spatial [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[96,346,519],"tags":[349,995,994],"_links":{"self":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2578"}],"collection":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2578"}],"version-history":[{"count":1,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2578\/revisions"}],"predecessor-version":[{"id":2579,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2578\/revisions\/2579"}],"wp:attachment":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2578"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2578"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2578"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}