{"id":2632,"date":"2022-05-08T10:15:50","date_gmt":"2022-05-08T00:15:50","guid":{"rendered":"https:\/\/www.cognav.net\/?p=2632"},"modified":"2022-05-08T10:15:50","modified_gmt":"2022-05-08T00:15:50","slug":"how-the-human-brain-represents-time-during-a-temporally-continuous-uninterrupted-experience","status":"publish","type":"post","link":"https:\/\/braininspirednavigation.com\/?p=2632","title":{"rendered":"How the human brain represents time during a temporally continuous uninterrupted experience?"},"content":{"rendered":"<p style=\"text-align: justify;\">Zahra M. Aghajan, Gabriel Kreiman, Itzhak Fried. <a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2022.05.05.490703v1\"><strong>Periodic Time Cells in Human Entorhinal Cortex<\/strong><\/a>.\u00a0bioRxiv 2022.05.05.490703; doi: https:\/\/doi.org\/10.1101\/2022.05.05.490703<\/p>\n<p style=\"text-align: justify;\">Abstract<br \/>\n&#8220;The representation of time in the brain is a fundamental component of cognition. <strong><span style=\"color: #ff0000;\">Here we investigated how the human brain represents time during a temporally continuous uninterrupted experience by presenting fifteen neurosurgical patients with an audiovisual video while recording neurons&#8217; activity from multiple brain regions<\/span><\/strong>. We report on <strong><span style=\"color: #ff0000;\">a set of units that modulate their activity in a strikingly periodic manner across different timescales\u2014from seconds to many minutes<\/span><\/strong>. These cells were most prevalent in the entorhinal cortex and time could be decoded from their population activity. Furthermore, <strong><span style=\"color: #ff0000;\">these cells remapped their dominant periodicity to shorter timescales during a subsequent recognition memory task<\/span><\/strong>. When the audiovisual sequence was presented at two different speeds (regular and faster), a significant percentage of these periodic time cells (PTCs) maintained their timescales, suggesting a degree of invariance with respect to the narrative content. <strong><span style=\"color: #ff0000;\">The temporal periodicity of PTCs may complement the spatial periodicity of grid cells, thereby providing scalable spatiotemporal metrics for encoding and retrieval of human experience<\/span><\/strong>.&#8221;<\/p>\n<p style=\"text-align: justify;\">Zahra M. Aghajan, Gabriel Kreiman, Itzhak Fried. <a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2022.05.05.490703v1\"><strong>Periodic Time Cells in Human Entorhinal Cortex<\/strong><\/a>.\u00a0bioRxiv 2022.05.05.490703; doi: https:\/\/doi.org\/10.1101\/2022.05.05.490703<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Zahra M. Aghajan, Gabriel Kreiman, Itzhak Fried. Periodic Time Cells in Human Entorhinal Cortex.\u00a0bioRxiv 2022.05.05.490703; doi: https:\/\/doi.org\/10.1101\/2022.05.05.490703 Abstract &#8220;The representation of time in the brain is a fundamental component of cognition. Here we investigated how the human brain represents time during a temporally continuous uninterrupted experience by presenting fifteen neurosurgical patients with an audiovisual video [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[346,762],"tags":[829,1016,1015,1017],"_links":{"self":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2632"}],"collection":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2632"}],"version-history":[{"count":1,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2632\/revisions"}],"predecessor-version":[{"id":2633,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2632\/revisions\/2633"}],"wp:attachment":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2632"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2632"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2632"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}