{"id":2677,"date":"2022-08-25T10:56:45","date_gmt":"2022-08-25T00:56:45","guid":{"rendered":"https:\/\/www.cognav.net\/?p=2677"},"modified":"2022-08-25T10:56:45","modified_gmt":"2022-08-25T00:56:45","slug":"how-brain-hippocampal-circuits-represent-switches-between-diferent-behaviours-rapidly-and-flexibility","status":"publish","type":"post","link":"https:\/\/braininspirednavigation.com\/?p=2677","title":{"rendered":"How brain hippocampal circuits represent switches between diferent behaviours rapidly and flexibility?"},"content":{"rendered":"<p style=\"text-align: justify;\">Ayelet Sarel, Shaked Palgi, Dan Blum, Johnatan Aljadeff, Liora Las &amp; Nachum Ulanovsky.\u00a0<a href=\"https:\/\/www.nature.com\/articles\/s41586-022-05112-2\"><strong>Natural switches in behaviour rapidly modulate hippocampal coding<\/strong><\/a>.\u00a0Nature\u00a0(2022). https:\/\/doi.org\/10.1038\/s41586-022-05112-2<\/p>\n<p style=\"text-align: justify;\">Abstract<br \/>\n&#8220;<strong><span style=\"color: #ff0000;\">Throughout their daily lives, animals and humans often switch between different behaviours<\/span><\/strong>. However, neuroscience research typically studies the brain while the animal is performing one behavioural task at a time, and <strong><span style=\"color: #ff0000;\">little is known about how brain circuits represent switches between different behaviours<\/span><\/strong>. Here we tested this question using an ethological setting: two bats flew together in a long 135\u2009m tunnel, and switched between navigation when flying alone (solo) and collision avoidance as they flew past each other (cross-over). Bats increased their echolocation click rate before each cross-over, indicating attention to the other bat1,2,3,4,5,6,7,8,9. <strong><span style=\"color: #ff0000;\">Hippocampal CA1 neurons represented the bat\u2019s own position when flying alone (place coding10,11,12,13,14). Notably, during cross-overs, neurons switched rapidly to jointly represent the interbat distance by self-position<\/span><\/strong>. <strong><span style=\"color: #ff0000;\">This neuronal switch was very fast\u2014as fast as 100\u2009ms\u2014which could be revealed owing to the very rapid natural behavioural switch<\/span><\/strong>. The neuronal switch correlated with the attention signal, as indexed by echolocation. Interestingly, <strong><span style=\"color: #ff0000;\">the different place fields of the same neuron often exhibited very different tuning to interbat distance, creating a complex non-separable coding of position by distance<\/span><\/strong>. Theoretical analysis showed that this complex representation yields more efficient coding. Overall, <strong><span style=\"color: #ff0000;\">our results suggest that during dynamic natural behaviour, hippocampal neurons can rapidly switch their core computation to represent the relevant behavioural variables, supporting behavioural flexibility<\/span><\/strong>.&#8221;<\/p>\n<p style=\"text-align: justify;\">Ayelet Sarel, Shaked Palgi, Dan Blum, Johnatan Aljadeff, Liora Las &amp; Nachum Ulanovsky.\u00a0<a href=\"https:\/\/www.nature.com\/articles\/s41586-022-05112-2\"><strong>Natural switches in behaviour rapidly modulate hippocampal coding<\/strong><\/a>.\u00a0Nature\u00a0(2022). https:\/\/doi.org\/10.1038\/s41586-022-05112-2<\/p>\n<p>&nbsp;<\/p>\n<p>News:\u00a0<\/p>\n<p><a href=\"https:\/\/wis-wander.weizmann.ac.il\/life-sciences\/neurons-caught-rapidly-switching-gears?utm_medium=social&amp;amp;utm_source=twitter&amp;amp;utm_campaign=neurons+rapidly+switching\">Neurons Caught Rapidly Switching Gears<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Ayelet Sarel, Shaked Palgi, Dan Blum, Johnatan Aljadeff, Liora Las &amp; Nachum Ulanovsky.\u00a0Natural switches in behaviour rapidly modulate hippocampal coding.\u00a0Nature\u00a0(2022). https:\/\/doi.org\/10.1038\/s41586-022-05112-2 Abstract &#8220;Throughout their daily lives, animals and humans often switch between different behaviours. However, neuroscience research typically studies the brain while the animal is performing one behavioural task at a time, and little is [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[987,96,346],"tags":[1055,1057,1054,1056],"_links":{"self":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2677"}],"collection":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2677"}],"version-history":[{"count":1,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2677\/revisions"}],"predecessor-version":[{"id":2678,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2677\/revisions\/2678"}],"wp:attachment":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2677"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2677"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2677"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}