{"id":2720,"date":"2022-10-06T11:35:56","date_gmt":"2022-10-06T01:35:56","guid":{"rendered":"https:\/\/www.cognav.net\/?p=2720"},"modified":"2022-10-06T11:35:56","modified_gmt":"2022-10-06T01:35:56","slug":"how-the-human-brain-mediates-second-scale-time-perception%ef%bc%9f","status":"publish","type":"post","link":"https:\/\/braininspirednavigation.com\/?p=2720","title":{"rendered":"How the human brain mediates second-scale time perception\uff1f"},"content":{"rendered":"<p style=\"text-align: justify;\">Yu, Q., Bi, Z., Jiang, S., Yan, B., Chen, H., Wang, Y., Miao, Y., Li, K., Wei, Z., Xie, Y. and Tan, X., 2022. <a href=\"https:\/\/doi.org\/10.1016\/j.neuron.2022.09.008\"><strong>Visual cortex encodes timing information in humans and mice<\/strong><\/a>. Neuron.DOI:https:\/\/doi.org\/10.1016\/j.neuron.2022.09.008<\/p>\n<p style=\"text-align: justify;\">Summary<br \/>\n\u201c<strong><span style=\"color: #ff0000;\">Despite the importance of timing in our daily lives, our understanding of how the human brain mediates second-scale time perception is limited<\/span><\/strong>. Here, we combined intracranial stereoelectroencephalography (SEEG) recordings in epileptic patients and circuit dissection in mice <strong><span style=\"color: #ff0000;\">to show that visual cortex (VC) encodes timing information<\/span><\/strong>. We first asked human participants to perform an interval-timing task and found VC to be a key timing brain area. We then conducted optogenetic experiments in mice and showed that VC plays an important role in the interval-timing behavior. <strong><span style=\"color: #ff0000;\">We further found that VC neurons fired in a time-keeping sequential manner and exhibited increased excitability in a timed manner<\/span><\/strong>. Finally, we used a computational model to illustrate a self-correcting learning process that generates interval-timed activities with scalar-timing property. <strong><span style=\"color: #ff0000;\">Our work reveals how localized oscillations in VC occurring in the seconds to deca-seconds range relate timing information from the external world to guide behavior<\/span><\/strong>.\u201d<\/p>\n<p style=\"text-align: justify;\">Yu, Q., Bi, Z., Jiang, S., Yan, B., Chen, H., Wang, Y., Miao, Y., Li, K., Wei, Z., Xie, Y. and Tan, X., 2022. <a href=\"https:\/\/doi.org\/10.1016\/j.neuron.2022.09.008\"><strong>Visual cortex encodes timing information in humans and mice<\/strong><\/a>. Neuron.DOI:https:\/\/doi.org\/10.1016\/j.neuron.2022.09.008<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Yu, Q., Bi, Z., Jiang, S., Yan, B., Chen, H., Wang, Y., Miao, Y., Li, K., Wei, Z., Xie, Y. and Tan, X., 2022. Visual cortex encodes timing information in humans and mice. Neuron.DOI:https:\/\/doi.org\/10.1016\/j.neuron.2022.09.008 Summary \u201cDespite the importance of timing in our daily lives, our understanding of how the human brain mediates second-scale time perception [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[987,96,762],"tags":[1102,1103,766,1101,652],"_links":{"self":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2720"}],"collection":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2720"}],"version-history":[{"count":1,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2720\/revisions"}],"predecessor-version":[{"id":2721,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2720\/revisions\/2721"}],"wp:attachment":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2720"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2720"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2720"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}