{"id":2731,"date":"2022-10-19T10:51:45","date_gmt":"2022-10-19T00:51:45","guid":{"rendered":"https:\/\/www.cognav.net\/?p=2731"},"modified":"2022-10-19T10:51:45","modified_gmt":"2022-10-19T00:51:45","slug":"how-to-integrate-new-memories-into-the-hippocampal-network-activity-space","status":"publish","type":"post","link":"https:\/\/braininspirednavigation.com\/?p=2731","title":{"rendered":"How to integrate new memories into the hippocampal network activity space?"},"content":{"rendered":"<p style=\"text-align: justify;\">Gava, G.P., McHugh, S.B., Lef\u00e8vre, L. et al. <a href=\"https:\/\/www.nature.com\/articles\/s41593-021-00804-w\"><strong>Integrating new memories into the hippocampal network activity space<\/strong><\/a>. Nat Neurosci 24, 326\u2013330 (2021). https:\/\/doi.org\/10.1038\/s41593-021-00804-w<\/p>\n<p style=\"text-align: justify;\">Abstract<br \/>\n&#8220;By investigating the topology of neuronal co-activity, we found that mnemonic information spans multiple operational axes in the mouse hippocampus network. <strong><span style=\"color: #ff0000;\">High-activity principal cells form the core of each memory along a first axis, segregating spatial contexts and novelty<\/span><\/strong>. <strong><span style=\"color: #ff0000;\">Low-activity cells join co-activity motifs across behavioral events and enable their crosstalk along two other axes<\/span><\/strong>. This reveals <strong><span style=\"color: #ff0000;\">an organizational principle for continuous integration and interaction of hippocampal memories<\/span><\/strong>.&#8221;<\/p>\n<p style=\"text-align: justify;\">Gava, G.P., McHugh, S.B., Lef\u00e8vre, L. et al. <a href=\"https:\/\/www.nature.com\/articles\/s41593-021-00804-w\"><strong>Integrating new memories into the hippocampal network activity space<\/strong><\/a>. Nat Neurosci 24, 326\u2013330 (2021). https:\/\/doi.org\/10.1038\/s41593-021-00804-w<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Gava, G.P., McHugh, S.B., Lef\u00e8vre, L. et al. Integrating new memories into the hippocampal network activity space. Nat Neurosci 24, 326\u2013330 (2021). https:\/\/doi.org\/10.1038\/s41593-021-00804-w Abstract &#8220;By investigating the topology of neuronal co-activity, we found that mnemonic information spans multiple operational axes in the mouse hippocampus network. High-activity principal cells form the core of each memory along [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[987,96,519],"tags":[1114,1113,1112],"_links":{"self":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2731"}],"collection":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2731"}],"version-history":[{"count":1,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2731\/revisions"}],"predecessor-version":[{"id":2732,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2731\/revisions\/2732"}],"wp:attachment":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2731"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2731"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2731"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}