{"id":2771,"date":"2023-01-15T11:19:58","date_gmt":"2023-01-15T01:19:58","guid":{"rendered":"https:\/\/www.cognav.net\/?p=2771"},"modified":"2023-01-15T11:19:58","modified_gmt":"2023-01-15T01:19:58","slug":"how-retrosplenial-cortex-computes-heading-direction-from-landmark-information","status":"publish","type":"post","link":"https:\/\/braininspirednavigation.com\/?p=2771","title":{"rendered":"How retrosplenial cortex computes heading direction from landmark information?"},"content":{"rendered":"<p style=\"text-align: justify;\">Eleonora Lomi, Kate Jeffery, Anna Mitchell. <a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2023.01.11.523585v1\"><strong>Convergence of direction, location and theta in the rat anteroventral thalamic nucleus<\/strong><\/a>. bioRxiv 2023.01.11.523585; doi: https:\/\/doi.org\/10.1101\/2023.01.11.523585<\/p>\n<p style=\"text-align: justify;\">Abstract<br \/>\n&#8220;<strong><span style=\"color: #ff0000;\">Retrosplenial cortex (RSC) is a cortical region that computes heading direction from landmark information, but how it does this remains unknown<\/span><\/strong>. Recently <strong><span style=\"color: #ff0000;\">we found that its two major subregions receive differential projections from two anteroventral thalamic (AV) subfields; dorsomedial (AVDM) and ventrolateral (AVVL)<\/span><\/strong>. To probe the respective contributions of these inputs we recorded single neurons and local field potentials from AV in rats during foraging. <strong><span style=\"color: #ff0000;\">We observed and characterized neurons modulated by theta oscillations, heading direction, and a conjunction of these<\/span><\/strong>. Unexpectedly, <strong><span style=\"color: #ff0000;\">we also discovered place cells (neurons modulated by location)<\/span><\/strong>. Consistent with the notion that AV contains two parallel subcircuits, there was a prevalence of non-conjunctive cells in AVDM, and of conjunctive and place neurons in AVVL. <strong><span style=\"color: #ff0000;\">This integration of spatial and movement signals in AV is consistent with a thalamic role in multimodal integration and may be important for supplying the spatial information that modulates RSC directional responding<\/span><\/strong>.&#8221;<\/p>\n<p style=\"text-align: justify;\">Eleonora Lomi, Kate Jeffery, Anna Mitchell. <a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2023.01.11.523585v1\"><strong>Convergence of direction, location and theta in the rat anteroventral thalamic nucleus<\/strong><\/a>. bioRxiv 2023.01.11.523585; doi: https:\/\/doi.org\/10.1101\/2023.01.11.523585<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Eleonora Lomi, Kate Jeffery, Anna Mitchell. Convergence of direction, location and theta in the rat anteroventral thalamic nucleus. bioRxiv 2023.01.11.523585; doi: https:\/\/doi.org\/10.1101\/2023.01.11.523585 Abstract &#8220;Retrosplenial cortex (RSC) is a cortical region that computes heading direction from landmark information, but how it does this remains unknown. Recently we found that its two major subregions receive differential projections [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[987,96,346],"tags":[1161,750,315,1159,1160],"_links":{"self":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2771"}],"collection":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2771"}],"version-history":[{"count":1,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2771\/revisions"}],"predecessor-version":[{"id":2772,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2771\/revisions\/2772"}],"wp:attachment":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2771"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2771"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2771"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}