{"id":2848,"date":"2023-04-04T10:48:24","date_gmt":"2023-04-04T00:48:24","guid":{"rendered":"https:\/\/www.cognav.net\/?p=2848"},"modified":"2023-04-04T10:48:24","modified_gmt":"2023-04-04T00:48:24","slug":"how-hippocampal-cognitive-maps-are-used-and-updated-fexibly-for-inference","status":"publish","type":"post","link":"https:\/\/braininspirednavigation.com\/?p=2848","title":{"rendered":"How hippocampal cognitive maps are used and updated fexibly for inference?"},"content":{"rendered":"<p style=\"text-align: justify;\">Mona M. Garvert, Tankred Saanum, Eric Schulz, Nicolas W. Schuck &amp; Christian F. Doeller. <a href=\"https:\/\/www.nature.com\/articles\/s41593-023-01283-x\"><strong>Hippocampal spatio-predictive cognitive maps adaptively guide reward generalization<\/strong><\/a>. Nat Neurosci (2023).<\/p>\n<p style=\"text-align: justify;\">Abstract<br \/>\n&#8220;The brain forms cognitive maps of relational knowledge\u2014an organizing principle thought to underlie our ability to generalize and make inferences. However, <strong><span style=\"color: #ff0000;\">how can a relevant map be selected in situations where a stimulus is embedded in multiple relational structures?<\/span> <\/strong>Here, <strong><span style=\"color: #ff0000;\">we find that both spatial and predictive cognitive maps influence generalization in a choice task, where spatial location determines reward magnitude<\/span><\/strong>. Mirroring behavior, <strong><span style=\"color: #ff0000;\">the hippocampus not only builds a map of spatial relationships but also encodes the experienced transition structure<\/span><\/strong>. As the task progresses, participants\u2019 choices become more influenced by spatial relationships, reflected in a strengthening of the spatial map and a weakening of the predictive map. This change is driven by orbitofrontal cortex, which represents the degree to which an outcome is consistent with the spatial rather than the predictive map and updates hippocampal representations accordingly. <strong><span style=\"color: #ff0000;\">Taken together, this demonstrates how hippocampal cognitive maps are used and updated flexibly for inference<\/span><\/strong>.&#8221;<\/p>\n<p style=\"text-align: justify;\">Mona M. Garvert, Tankred Saanum, Eric Schulz, Nicolas W. Schuck &amp; Christian F. Doeller. <a href=\"https:\/\/www.nature.com\/articles\/s41593-023-01283-x\"><strong>Hippocampal spatio-predictive cognitive maps adaptively guide reward generalization<\/strong><\/a>. Nat Neurosci (2023).<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Mona M. Garvert, Tankred Saanum, Eric Schulz, Nicolas W. Schuck &amp; Christian F. Doeller. Hippocampal spatio-predictive cognitive maps adaptively guide reward generalization. Nat Neurosci (2023). Abstract &#8220;The brain forms cognitive maps of relational knowledge\u2014an organizing principle thought to underlie our ability to generalize and make inferences. However, how can a relevant map be selected in [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[987,346],"tags":[147,998,1232],"_links":{"self":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2848"}],"collection":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2848"}],"version-history":[{"count":1,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2848\/revisions"}],"predecessor-version":[{"id":2849,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2848\/revisions\/2849"}],"wp:attachment":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2848"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2848"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2848"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}