{"id":2932,"date":"2024-02-01T13:59:04","date_gmt":"2024-02-01T03:59:04","guid":{"rendered":"https:\/\/www.cognav.net\/?p=2932"},"modified":"2024-02-01T13:59:04","modified_gmt":"2024-02-01T03:59:04","slug":"how-to-implement-distinct-manifold-encoding-of-navigational-information-in-the-subiculum-and-hippocampus","status":"publish","type":"post","link":"https:\/\/braininspirednavigation.com\/?p=2932","title":{"rendered":"How to implement distinct manifold encoding of navigational information in the subiculum and hippocampus?"},"content":{"rendered":"<p style=\"text-align: justify;\">Shinya Nakai, Takuma Kitanishi, Kenji Mizuseki. <strong><a href=\"https:\/\/www.science.org\/doi\/10.1126\/sciadv.adi4471\">Distinct manifold encoding of navigational information in the subiculum and hippocampus<\/a><\/strong>. Science Advances, 10,eadi4471(2024).DOI:10.1126\/sciadv.adi4471<\/p>\n<p style=\"text-align: justify;\">Abstract<br \/>\n&#8220;<span style=\"color: #ff0000;\"><strong>The subiculum (SUB) plays a crucial role in spatial navigation and encodes navigational information differently from the hippocampal CA1 area<\/strong><\/span>. However, <strong><span style=\"color: #ff0000;\">the representation of subicular population activity remains unknown<\/span><\/strong>. Here, we investigated the neuronal population activity recorded extracellularly from the CA1 and SUB of rats performing T-maze and open-field tasks. The trajectory of population activity in both areas was confined to low-dimensional neural manifolds homoeomorphic to external space. <strong><span style=\"color: #ff0000;\">The manifolds conveyed position, speed, and future path information with higher decoding accuracy in the SUB than in the CA1<\/span><\/strong>. The manifolds exhibited common geometry across rats and regions for the CA1 and SUB and between tasks in the SUB. During post-task ripples in slow-wave sleep, population activity represented reward locations\/events more frequently in the SUB than in CA1. Thus, <strong><span style=\"color: #ff0000;\">the CA1 and SUB encode information distinctly into the neural manifolds that underlie navigational information processing during wakefulness and sleep<\/span><\/strong>.&#8221;<\/p>\n<p style=\"text-align: justify;\">Shinya Nakai, Takuma Kitanishi, Kenji Mizuseki. <strong><a href=\"https:\/\/www.science.org\/doi\/10.1126\/sciadv.adi4471\">Distinct manifold encoding of navigational information in the subiculum and hippocampus<\/a><\/strong>. Science Advances, 10,eadi4471(2024).DOI:10.1126\/sciadv.adi4471<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Shinya Nakai, Takuma Kitanishi, Kenji Mizuseki. Distinct manifold encoding of navigational information in the subiculum and hippocampus. Science Advances, 10,eadi4471(2024).DOI:10.1126\/sciadv.adi4471 Abstract &#8220;The subiculum (SUB) plays a crucial role in spatial navigation and encodes navigational information differently from the hippocampal CA1 area. However, the representation of subicular population activity remains unknown. Here, we investigated the neuronal [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[96,346],"tags":[1283,349,1284,903],"_links":{"self":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2932"}],"collection":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2932"}],"version-history":[{"count":1,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2932\/revisions"}],"predecessor-version":[{"id":2933,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2932\/revisions\/2933"}],"wp:attachment":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2932"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2932"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2932"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}