{"id":2952,"date":"2024-04-01T12:08:47","date_gmt":"2024-04-01T02:08:47","guid":{"rendered":"https:\/\/www.cognav.net\/?p=2952"},"modified":"2024-04-01T12:26:18","modified_gmt":"2024-04-01T02:26:18","slug":"how-does-the-brain-select-what-to-remember-during-sleep","status":"publish","type":"post","link":"https:\/\/braininspirednavigation.com\/?p=2952","title":{"rendered":"How hippocampal activity encodes numerous memories of specific events in life?"},"content":{"rendered":"<p style=\"text-align: justify;\">Selmaan N. Chettih,Emily L. Mackevicius,Stephanie Hale,Dmitriy Aronov. <strong><a href=\"https:\/\/www.cell.com\/cell\/fulltext\/S0092-8674%2824%2900235-6\">Barcoding of episodic memories in the hippocampus of a food-caching bird<\/a><\/strong>. Cell, March 29, 2024.\u00a0 DOI:https:\/\/doi.org\/10.1016\/j.cell.2024.02.032<\/p>\n<p style=\"text-align: justify;\">Summary<br \/>\n\u201c<strong><span style=\"color: #ff0000;\">The hippocampus is critical for episodic memory<\/span><\/strong>. Although hippocampal activity represents place and other behaviorally relevant variables, <strong><span style=\"color: #ff0000;\">it is unclear how it encodes numerous memories of specific events in life<\/span><\/strong>. To study episodic coding, we leveraged the specialized behavior of chickadees\u2014food-caching birds that form memories at well-defined moments in time whenever they cache food for subsequent retrieval. Our recordings during caching revealed very sparse, transient barcode-like patterns of firing across hippocampal neurons. <strong><span style=\"color: #ff0000;\">Each \u201cbarcode\u201d uniquely represented a caching event and transiently reactivated during the retrieval of that specific cache<\/span><\/strong>. Barcodes co-occurred with the conventional activity of place cells but were uncorrelated even for nearby cache locations that had similar place codes. <strong><span style=\"color: #ff0000;\">We propose that animals recall episodic memories by reactivating hippocampal barcodes<\/span><\/strong>. Similarly to computer hash codes, <strong><span style=\"color: #ff0000;\">these patterns assign unique identifiers to different events and could be a mechanism for rapid formation and storage of many non-interfering memories<\/span><\/strong>.\u201d<\/p>\n<p style=\"text-align: justify;\">Selmaan N. Chettih,Emily L. Mackevicius,Stephanie Hale,Dmitriy Aronov. <strong><a href=\"https:\/\/www.cell.com\/cell\/fulltext\/S0092-8674%2824%2900235-6\">Barcoding of episodic memories in the hippocampus of a food-caching bird<\/a><\/strong>. Cell, March 29, 2024.\u00a0 DOI:https:\/\/doi.org\/10.1016\/j.cell.2024.02.032<\/p>\n<p style=\"text-align: justify;\">\u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Selmaan N. Chettih,Emily L. Mackevicius,Stephanie Hale,Dmitriy Aronov. Barcoding of episodic memories in the hippocampus of a food-caching bird. Cell, March 29, 2024.\u00a0 DOI:https:\/\/doi.org\/10.1016\/j.cell.2024.02.032 Summary \u201cThe hippocampus is critical for episodic memory. Although hippocampal activity represents place and other behaviorally relevant variables, it is unclear how it encodes numerous memories of specific events in life. To [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[96,636,346],"tags":[],"_links":{"self":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2952"}],"collection":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2952"}],"version-history":[{"count":3,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2952\/revisions"}],"predecessor-version":[{"id":2956,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2952\/revisions\/2956"}],"wp:attachment":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2952"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2952"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2952"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}