{"id":2957,"date":"2024-04-01T12:29:44","date_gmt":"2024-04-01T02:29:44","guid":{"rendered":"https:\/\/www.cognav.net\/?p=2957"},"modified":"2024-04-01T12:30:08","modified_gmt":"2024-04-01T02:30:08","slug":"how-does-the-brain-select-what-to-remember-during-sleep-2","status":"publish","type":"post","link":"https:\/\/braininspirednavigation.com\/?p=2957","title":{"rendered":"How does the brain select what to remember during sleep?"},"content":{"rendered":"<p style=\"text-align: justify;\">Wannan Yang, Chen Sun, Roman Husz\u00e1r, Thomas Hainmueller, Kirill Kiselev, Gy\u00f6rgy Buzs\u00e1ki. \u201c<strong><a href=\"https:\/\/www.science.org\/doi\/10.1126\/science.adk8261\">Selection of experience for memory by hippocampal sharp wave ripple<\/a><\/strong>.\u201d\u00a0<em>Science<\/em>\u00a0<strong>383<\/strong>, 1478-1483 (2024).<\/p>\n<p style=\"text-align: justify;\">Abstract<br \/>\n&#8220;<strong><span style=\"color: #ff0000;\">Experiences need to be tagged during learning for further consolidation<\/span><\/strong>. However, <strong><span style=\"color: #ff0000;\">neurophysiological mechanisms that select experiences for lasting memory are not known<\/span><\/strong>. By combining large-scale neural recordings in mice with dimensionality reduction techniques, <strong><span style=\"color: #ff0000;\">we observed that successive maze traversals were tracked by continuously drifting populations of neurons, providing neuronal signatures of both places visited and events encountered<\/span><\/strong>. When the brain state changed during reward consumption, sharp wave ripples (SPW-Rs) occurred on some trials, and their specific spike content decoded the trial blocks that surrounded them. During postexperience sleep, SPW-Rs continued to replay those trial blocks that were reactivated most frequently during waking SPW-Rs. <strong><span style=\"color: #ff0000;\">Replay content of awake SPW-Rs may thus provide a neurophysiological tagging mechanism to select aspects of experience that are preserved and consolidated for future use<\/span><\/strong>.&#8221;<\/p>\n<p style=\"text-align: justify;\">Wannan Yang, Chen Sun, Roman Husz\u00e1r, Thomas Hainmueller, Kirill Kiselev, Gy\u00f6rgy Buzs\u00e1ki. \u201c<strong><a href=\"https:\/\/www.science.org\/doi\/10.1126\/science.adk8261\">Selection of experience for memory by hippocampal sharp wave ripple<\/a><\/strong>.\u201d\u00a0<em>Science<\/em>\u00a0<strong>383<\/strong>, 1478-1483 (2024).<\/p>\n<p style=\"text-align: justify;\"><a href=\"https:\/\/winnieyangwannan.github.io\/RippleTagging\/\">https:\/\/winnieyangwannan.github.io\/RippleTagging\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Wannan Yang, Chen Sun, Roman Husz\u00e1r, Thomas Hainmueller, Kirill Kiselev, Gy\u00f6rgy Buzs\u00e1ki. \u201cSelection of experience for memory by hippocampal sharp wave ripple.\u201d\u00a0Science\u00a0383, 1478-1483 (2024). Abstract &#8220;Experiences need to be tagged during learning for further consolidation. However, neurophysiological mechanisms that select experiences for lasting memory are not known. By combining large-scale neural recordings in mice with [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[96,636],"tags":[499,875,258,148,1303],"_links":{"self":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2957"}],"collection":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2957"}],"version-history":[{"count":2,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2957\/revisions"}],"predecessor-version":[{"id":2959,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2957\/revisions\/2959"}],"wp:attachment":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2957"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2957"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2957"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}