{"id":2979,"date":"2024-06-19T13:25:49","date_gmt":"2024-06-19T03:25:49","guid":{"rendered":"https:\/\/www.cognav.net\/?p=2979"},"modified":"2024-06-19T13:25:49","modified_gmt":"2024-06-19T03:25:49","slug":"whats-the-human-neural-dynamics-of-real-world-and-imagined-navigation","status":"publish","type":"post","link":"https:\/\/braininspirednavigation.com\/?p=2979","title":{"rendered":"What&#8217;s the human neural dynamics of real-world and imagined navigation?"},"content":{"rendered":"<p style=\"text-align: justify;\">Martin Seeber, Matthias Stangl, Mauricio Vallejo, Uros Topalovic, Sonja Hiller, Casey H. Halpern, Jean-Philippe Langevin, Vikram R. Rao, Itzhak Fried, Dawn Eliashiv, Nanthia Suthana. <a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2024.05.23.595237v1\"><strong>Human neural dynamics of real-world and imagined navigation<\/strong><\/a>. bioRxiv 2024.05.23.595237; doi: https:\/\/doi.org\/10.1101\/2024.05.23.595237<\/p>\n<p style=\"text-align: justify;\">Summary<br \/>\n&#8220;<strong><span style=\"color: #ff0000;\">The ability to form episodic memories and later imagine them is integral to the human experience, influencing our recollection of the past and our ability to envision the future<\/span><\/strong>. While research on spatial navigation in rodents suggests the involvement of the medial temporal lobe (MTL), especially the hippocampus, in these cognitive functions, <strong><span style=\"color: #ff0000;\">it is uncertain if these insights apply to the human MTL, especially regarding imagination and the reliving of events<\/span><\/strong>. Importantly, by involving human participants, imaginations can be explicitly instructed and their mental experiences verbally reported. In this study, <strong><span style=\"color: #ff0000;\">we investigated the role of hippocampal theta oscillations in both real-world and imagined navigatio<\/span><\/strong>n, leveraging motion capture and intracranial electroencephalographic recordings from individuals with chronically implanted MTL electrodes who could move freely. <strong><span style=\"color: #ff0000;\">Our results revealed intermittent theta dynamics, particularly within the hippocampus, which encoded spatial geometry and partitioned navigational routes into linear segments during real-world navigation<\/span><\/strong>. During imagined navigation, theta dynamics exhibited similar, repetitive patterns despite the absence of external environmental cues. Furthermore, a computational model, generalizing from real-world to imagined navigation, successfully reconstructed participants\u2019 imagined positions using neural data. These findings offer unique insights into <strong><span style=\"color: #ff0000;\">the neural mechanisms underlying human navigation and imagination, with implications for understanding episodic memory formation and retrieval in real-world settings<\/span><\/strong>.&#8221;<\/p>\n<p style=\"text-align: justify;\">Martin Seeber, Matthias Stangl, Mauricio Vallejo, Uros Topalovic, Sonja Hiller, Casey H. Halpern, Jean-Philippe Langevin, Vikram R. Rao, Itzhak Fried, Dawn Eliashiv, Nanthia Suthana. <a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2024.05.23.595237v1\"><strong>Human neural dynamics of real-world and imagined navigation<\/strong><\/a>. bioRxiv 2024.05.23.595237; doi: https:\/\/doi.org\/10.1101\/2024.05.23.595237<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Martin Seeber, Matthias Stangl, Mauricio Vallejo, Uros Topalovic, Sonja Hiller, Casey H. Halpern, Jean-Philippe Langevin, Vikram R. Rao, Itzhak Fried, Dawn Eliashiv, Nanthia Suthana. Human neural dynamics of real-world and imagined navigation. bioRxiv 2024.05.23.595237; doi: https:\/\/doi.org\/10.1101\/2024.05.23.595237 Summary &#8220;The ability to form episodic memories and later imagine them is integral to the human experience, influencing our [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[96,346],"tags":[1316,367,1258],"_links":{"self":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2979"}],"collection":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2979"}],"version-history":[{"count":1,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2979\/revisions"}],"predecessor-version":[{"id":2980,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2979\/revisions\/2980"}],"wp:attachment":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2979"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2979"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2979"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}