{"id":2990,"date":"2024-07-14T10:10:40","date_gmt":"2024-07-14T00:10:40","guid":{"rendered":"https:\/\/www.cognav.net\/?p=2990"},"modified":"2024-07-14T10:10:40","modified_gmt":"2024-07-14T00:10:40","slug":"how-hippocampal-entorhinal-cognitive-maps-and-cortical-motor-system-represent-action-plans-and-their-outcomes","status":"publish","type":"post","link":"https:\/\/braininspirednavigation.com\/?p=2990","title":{"rendered":"How hippocampal-entorhinal cognitive maps and cortical motor system represent action plans and their outcomes?"},"content":{"rendered":"<p style=\"text-align: justify;\">Irina Barnaveli, Simone Vigan\u00f2, Daniel Reznik, Patrick Haggard, Christian F. Doeller. <a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2024.07.04.602119v1\"><strong>Hippocampal-entorhinal cognitive maps and cortical motor system represent action plans and their outcomes<\/strong><\/a>. bioRxiv 2024.07.04.602119; doi: https:\/\/doi.org\/10.1101\/2024.07.04.602119<\/p>\n<p style=\"text-align: justify;\">&#8220;<strong><span style=\"color: #ff0000;\">Efficiently interacting with the environment requires weighing and selecting among multiple alternative actions based on their associated outcomes<\/span><\/strong>. However, <strong><span style=\"color: #ff0000;\">the neural mechanisms underlying these processes are still debated<\/span><\/strong>. We showed that <strong><span style=\"color: #ff0000;\">forming relations between arbitrary action-outcome associations involved building a cognitive map<\/span><\/strong>. Using a novel immersive virtual reality paradigm, participants learned 2D abstract motor action-outcome associations and later compared action combinations while their brain activity was monitored with fMRI. <strong><span style=\"color: #ff0000;\">We observed a hexadirectional modulation of the activity in entorhinal cortex while participants compared different action plans<\/span><\/strong>. Furthermore, hippocampal activity scaled with the 2D similarity between outcomes of these action plans. Conversely, the supplementary motor area (SMA) represented individual actions, showing a stronger response to overlapping action plans. Crucially, the connectivity between hippocampus and SMA was modulated by the similarity between the action plans, suggesting their complementary roles in action evaluation. <strong><span style=\"color: #ff0000;\">These findings provide evidence for the role of cognitive maps in action selection, challenging classical models of memory taxonomy and its neural bases<\/span><\/strong>.&#8221;<\/p>\n<p style=\"text-align: justify;\">Irina Barnaveli, Simone Vigan\u00f2, Daniel Reznik, Patrick Haggard, Christian F. Doeller. <a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2024.07.04.602119v1\"><strong>Hippocampal-entorhinal cognitive maps and cortical motor system represent action plans and their outcomes<\/strong><\/a>. bioRxiv 2024.07.04.602119; doi: https:\/\/doi.org\/10.1101\/2024.07.04.602119<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Irina Barnaveli, Simone Vigan\u00f2, Daniel Reznik, Patrick Haggard, Christian F. Doeller. Hippocampal-entorhinal cognitive maps and cortical motor system represent action plans and their outcomes. bioRxiv 2024.07.04.602119; doi: https:\/\/doi.org\/10.1101\/2024.07.04.602119 &#8220;Efficiently interacting with the environment requires weighing and selecting among multiple alternative actions based on their associated outcomes. However, the neural mechanisms underlying these processes are still [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[987,96,346,419],"tags":[1324,1326,1140,1323,1322,1325],"_links":{"self":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2990"}],"collection":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2990"}],"version-history":[{"count":1,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2990\/revisions"}],"predecessor-version":[{"id":2991,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/2990\/revisions\/2991"}],"wp:attachment":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2990"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2990"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2990"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}