{"id":3015,"date":"2024-08-14T18:58:05","date_gmt":"2024-08-14T08:58:05","guid":{"rendered":"https:\/\/www.cognav.net\/?p=3015"},"modified":"2024-08-14T18:58:05","modified_gmt":"2024-08-14T08:58:05","slug":"how-the-brain-merge-information-from-across-sensory-modalities","status":"publish","type":"post","link":"https:\/\/braininspirednavigation.com\/?p=3015","title":{"rendered":"How the brain merge information from across sensory modalities?"},"content":{"rendered":"<p style=\"text-align: justify;\">Daniel D Kato, Randy M Bruno. <a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2024.08.07.607026v1\"><strong>Stability of cross-sensory input to primary somatosensory cortex across experience<\/strong><\/a>. bioRxiv 2024.08.07.607026; doi: https:\/\/doi.org\/10.1101\/2024.08.07.607026<\/p>\n<p style=\"text-align: justify;\">Abstract<br \/>\n&#8220;<strong><span style=\"color: #ff0000;\">Merging information from across sensory modalities is key to forming robust, disambiguated percepts of the world<\/span><\/strong>, yet<strong><span style=\"color: #ff0000;\"> how the brain achieves this feat remains unclear<\/span><\/strong>. Recent observations of <strong><span style=\"color: #ff0000;\">cross-modal influences in primary sensory cortical areas have suggested that multisensory integration may occur in the earliest stages of cortical processing<\/span><\/strong>, but the <strong><span style=\"color: #ff0000;\">role of these responses is still poorly understood<\/span><\/strong>. We address these questions by testing several hypotheses about the possible functions served by auditory influences on the barrel field of mouse primary somatosensory cortex (S1) using in vivo 2-photon calcium imaging. We observed sound-evoked spiking activity in a small fraction of cells overall, and moreover that this sparse activity was insufficient to encode auditory stimulus identity; few cells responded preferentially to one sound or another, and a linear classifier trained to decode auditory stimuli from population activity performed barely above chance. Moreover S1 did not encode information about specific audio-tactile feature conjunctions that we tested. Our ability to decode auditory audio-tactile stimuli from neural activity remained unchanged after both passive experience and reinforcement. Collectively, <strong><span style=\"color: #ff0000;\">these results suggest that while a primary sensory cortex is highly plastic with regard to its own modality, the influence of other modalities are remarkably stable and play a largely stimulus-non-specific role<\/span><\/strong>.&#8221;<\/p>\n<p style=\"text-align: justify;\">Daniel D Kato, Randy M Bruno. <a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2024.08.07.607026v1\"><strong>Stability of cross-sensory input to primary somatosensory cortex across experience<\/strong><\/a>. bioRxiv 2024.08.07.607026; doi: https:\/\/doi.org\/10.1101\/2024.08.07.607026<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Daniel D Kato, Randy M Bruno. Stability of cross-sensory input to primary somatosensory cortex across experience. bioRxiv 2024.08.07.607026; doi: https:\/\/doi.org\/10.1101\/2024.08.07.607026 Abstract &#8220;Merging information from across sensory modalities is key to forming robust, disambiguated percepts of the world, yet how the brain achieves this feat remains unclear. Recent observations of cross-modal influences in primary sensory cortical [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[96],"tags":[1340],"_links":{"self":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/3015"}],"collection":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=3015"}],"version-history":[{"count":1,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/3015\/revisions"}],"predecessor-version":[{"id":3016,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=\/wp\/v2\/posts\/3015\/revisions\/3016"}],"wp:attachment":[{"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=3015"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=3015"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/braininspirednavigation.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=3015"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}