Category: Cognitive Navigation

Whether and how the 3D position and velocity of the head and eyes are represented in the rodent MEC neural circuitry supporting navigation?

Caitlin S. Mallory, Kiah Hardcastle, Malcolm G. Campbell, Alexander Attinger, Isabel I. C. Low, Jennifer L. Raymond & Lisa M. Giocomo. Mouse entorhinal cortex encodes a diverse repertoire of self-motion signals. Nat Commun 12, 671 (2021). https://doi.org/10.1038/s41467-021-20936-8

Abstract
“Neural …

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How does the retrosplenial cortex combine internal and external cues to encode head velocity during navigation?

Sepiedeh Keshavarzi, Edward F. Bracey, Richard A. Faville, Dario Campagner, Adam L. Tyson, Stephen C. Lenzi, Tiago Branco, Troy W. Margrie. The retrosplenial cortex combines internal and external cues to encode head velocity during navigation. bioRxiv 2021.01.22.427789; doi: https://doi.org/10.1101/2021.01.22.427789…

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How does the brain represent the location of oneself and others in shared environments?

Stangl, M., Topalovic, U., Inman, C.S. et al. Boundary-anchored neural mechanisms of location-encoding for self and others. Nature (2020). https://doi.org/10.1038/s41586-020-03073-y

Abstract
Everyday tasks in social settings require humans to encode neural representations of not only their own spatial

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How does the brain update memory representation?

William Mau, Michael E Hasselmo, Denise J Cai. The brain in motion: How ensemble fluidity drives memory-updating and flexibility
eLife 2020;9:e63550 DOI: 10.7554/eLife.63550

Abstract
“While memories are often thought of as flashbacks to a previous experience, they do not …

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How do time cells in the human hippocampus and entorhinal cortex support episodic memory?

Gray Umbach, Pranish Kantak, Joshua Jacobs, Michael Kahana, Brad E. Pfeiffer, Michael Sperling, Bradley Lega. Time cells in the human hippocampus and entorhinal cortex support episodic memory. Proceedings of the National Academy of Sciences Nov 2020, 117 (45) 28463-28474; …

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How do hippocampal replay patterns dynamically change during the spatial learning process

Hideyoshi Igata, Yuji Ikegaya, Takuya Sasaki. Prioritized experience replays on a hippocampal predictive map for learning. Proceedings of the National Academy of Sciences Jan 2021, 118 (1) e2011266118; DOI: 10.1073/pnas.2011266118

Significance

The hippocampus is crucial for spatial learning

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How to implement sensory processing, learning, and motor control using a biologically spiking neural network model of the flying insect mushroom body?

Hannes Rapp, Martin Paul Nawrot. A spiking neural program for sensorimotor control during foraging in flying insects. Proceedings of the National Academy of Sciences Nov 2020, 117 (45) 28412-28421; DOI: 10.1073/pnas.2009821117

Significance

Living organisms demonstrate remarkable abilities in

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How does the brain integrate self-motion and goals adaptively?

Andrew S. Alexander, Janet C. Tung, G. William Chapman, Laura E. Shelley, Michael E. Hasselmo, Douglas A. Nitz. Adaptive integration of self-motion and goals in posterior parietal cortexbioRxiv 2020.12.19.423589; doi: https://doi.org/10.1101/2020.12.19.423589

Abstract
Animals engage in a variety

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How does the brain encode abstract state-space representations in high-dimensional environments?

Cross L, Cockburn J, Yue Y, O’Doherty JP. Using deep reinforcement learning to reveal how the brain encodes abstract state-space representations in high-dimensional environments. Neuron. 2020 Dec 7:S0896-6273(20)30899-0. doi: 10.1016/j.neuron.2020.11.021.

In Brief
Cross et al. scanned humans playing

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How does the monkey brain represent what and when conjunctively during anassociative memory task?

Cruzado NA, Tiganj Z, Brincat SL, Miller EK, Howard MW. Conjunctive representation of what and when in monkey hippocampus and lateral prefrontal cortex during an associative memory task. Hippocampus. 2020 Dec;30(12):1332-1346. doi: 10.1002/hipo.23282.

Abstract
Adaptive memory requires the

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How do hippocampal place cells support spatial navigation and memory?

Nick T.M. Robinson, Lucie A.L. Descamps, Lloyd E. Russell, Moritz O. Buchholz, Brendan A. Bicknell, Georgy K. Antonov, Joanna Y.N. Lau, Rebecca Nutbrown, Christoph Schmidt-Hieber, Michael Häusser. Targeted Activation of Hippocampal Place Cells Drives Memory-Guided Spatial Behavior. Cell, 2020, …

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How does the brain implement allocentric-egocentric coordinate transformation to guide navigation behavior?

Joeri BG van Wijngaarden, Susanne S Babl, Hiroshi T Ito. Entorhinal-retrosplenial circuits for allocentric-egocentric transformation of boundary coding. Elife. 2020 Nov 3;9:e59816. doi: 10.7554/eLife.59816. PMID: 33138915.

Abstract
Spatial navigation requires landmark coding from two perspectives, relying on viewpoint-invariant

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Whether do the dorsal CA1 place cells of rats encode environmental connectivity?

Éléonore Duvelle, Roddy M Grieves, Anyi Liu, Selim Jedidi-Ayoub, Joanna Holeniewska, Adam Harris, Nils Nyberg, Francesco Donnarumma, Julie M. Lefort, Kate J. Jeffery, Christopher Summerfield, Giovanni Pezzulo, Hugo J. Spiers. Hippocampal place cells encode global location but not changes in

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How do rats navigate in three-dimensional volumetric environments?

Selim Jedidi-Ayoub, Karyna Mishchanchuk, Anyi Liu, Sophie Renaudineau, Éléonore Duvelle & Roddy M. Grieves. Volumetric spatial behaviour in rats reveals the anisotropic organisation of navigation. Anim Cogn (2020). https://doi.org/10.1007/s10071-020-01432-w

Abstract
“We investigated how access to the vertical dimension influences …

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How does brainstem locomotor circuit drive the activity of speed cells in the medial entorhinal cortex?

Carvalho, Miguel M., Nouk Tanke, Emilio Kropff, Menno P. Witter, May-Britt Moser, and Edvard I. Moser. “A Brainstem Locomotor Circuit Drives the Activity of Speed Cells in the Medial Entorhinal Cortex.” Cell Reports 32, no. 10 (2020): 108123.…

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