Tag: Time Cells

How medial entorhinal cortex mediates learning of context-dependent interval timing behavior?

Bigus, E.R., Lee, HW., Bowler, J.C. et al. Medial entorhinal cortex mediates learning of context-dependent interval timing behavior. Nat Neurosci (2024). https://doi.org/10.1038/s41593-024-01683-7

Abstract
Episodic memory requires encoding the temporal structure of experience and relies on brain circuits in

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Which neural circuits utilize relevant cues to initiate integration?

Raphael Heldman, Dongyan Pang, Xiaoliang Zhao, Yingxue Wang. A CA1 circuit motif that signals the start of information integration. bioRxiv 2023.03.12.532295; doi: https://doi.org/10.1101/2023.03.12.532295

Abstract
Integrating information from the recent past is critical for guiding predictions and shaping behavior

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Whether hippocampal time cells represent context-dependent experience or time per se?

David B. Omer, Liora Las & Nachum Ulanovsky. Contextual and pure time coding for self and other in the hippocampus. Nat Neurosci (2022). https://doi.org/10.1038/s41593-022-01226-y

Abstract
“Navigation and episodic memory depend critically on representing temporal sequences. Hippocampal ‘time cells’ form

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How the human brain mediates second-scale time perception?

Yu, Q., Bi, Z., Jiang, S., Yan, B., Chen, H., Wang, Y., Miao, Y., Li, K., Wei, Z., Xie, Y. and Tan, X., 2022. Visual cortex encodes timing information in humans and mice. Neuron.DOI:https://doi.org/10.1016/j.neuron.2022.09.008

Summary
Despite the importance

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Whether the compression of time cells obeys the Weber-Fechner Law?

Rui Cao, John H. Bladon, Stephen J. Charczynski, Michael E. Hasselmo, Marc W. Howard. Internally Generated Time in the Rodent Hippocampus is Logarithmically Compressed. bioRxiv 2021.10.25.465750; doi: https://doi.org/10.1101/2021.10.25.465750

Abstract
“The Weber-Fechner law proposes that our perceived sensory input increases …

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How the time is encoded in rat dorsolateral striatum?

Alessandro Toso, Sebastian Reinartz, Francesca Pulecchi, Mathew E. Diamond. Time coding in rat dorsolateral striatum. Neuron, 2021, https://doi.org/10.1016/j.neuron.2021.08.020.

Summary
To assess the role of dorsolateral striatum (DLS) in time coding, we recorded neuronal activity in rats tasked with

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How do time cells in the human hippocampus and entorhinal cortex support episodic memory?

Gray Umbach, Pranish Kantak, Joshua Jacobs, Michael Kahana, Brad E. Pfeiffer, Michael Sperling, Bradley Lega. Time cells in the human hippocampus and entorhinal cortex support episodic memory. Proceedings of the National Academy of Sciences Nov 2020, 117 (45) 28463-28474; …

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