Category: Spatial Memory

How flexible navigation strategies emerge and evolve in freely moving non-human primates?

Nada El Mahmoudi, Francesca Lanzarini, Farzad Ziaie Nezhad, Deepak Surendran, Jean Laurens. From Exploration to Structured Navigation: Learning Dynamics of Freely Moving Marmosets during Foraging. bioRxiv 2025.03.22.644580; doi: https://doi.org/10.1101/2025.03.22.644580

Abstract
Spatial memory plays a crucial role in guiding

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Whether and how dendritic plasticity modulates memory?

Sehgal, M., Filho, D.A., Kastellakis, G. et al. Compartmentalized dendritic plasticity in the mouse retrosplenial cortex links contextual memories formed close in time. Nat Neurosci (2025). https://doi.org/10.1038/s41593-025-01876-8

Abstract
Events occurring close in time are often linked in memory

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How does the brain actually represent the real world with its complex, multianimal settings?

Saikat Ray, Itay Yona, Nadav Elami, Shaked Palgi, Kenneth W. Latimer, Bente Jacobsen, Menno P. Witter, Liora Las, and Nachum Ulanovsky. Hippocampal coding of identity, sex, hierarchy, and affiliation in a social group of wild fruit bats. Science 387,eadk9385(2025). …

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How does one brain circuit encode memories of both places and events?

Sarthak Chandra, Sugandha Sharma, Rishidev Chaudhuri & Ila Fiete. Episodic and associative memory from spatial scaffolds in the hippocampus. Nature (2025). https://doi.org/10.1038/s41586-024-08392-y

Abstract
“Hippocampal circuits in the brain enable two distinct cognitive functions: the construction of spatial maps for

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How sleep microstructure organizes memory replay?

Hongyu Chang, Wenbo Tang, Annabella M. Wulf, Thokozile Nyasulu, Madison E. Wolf, Antonio Fernandez-Ruiz & Azahara Oliva. Sleep microstructure organizes memory replay. Nature (2025). https://doi.org/10.1038/s41586-024-08340-w

Abstract
“Recently acquired memories are reactivated in the hippocampus during sleep, an initial step …

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How to understand the neural basis of natural intelligence?

Angelo Forli, Michael M. Yartsev. Understanding the neural basis of natural intelligence. Cell, 2024, Volume 187, Issue 21, 5833 – 5837

Abstract
Understanding the neural basis of natural intelligence necessitates a paradigm shift: from strict reductionism toward …

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How human hippocampal CA3 uses specific functional connectivity rules for efficient associative memory?

Jake F. Watson, Victor Vargas-Barroso, Rebecca J. Morse-Mora, Andrea Navas-Olive, Mojtaba R. Tavakoli, Johann G. Danzl, Matthias Tomschik, Karl Rössler, Peter Jonas. Human hippocampal CA3 uses specific functional connectivity rules for efficient associative memory. Cell, 2024. DOI: 10.1016/j.cell.2024.11.022

Summary…

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How are associative memories formed? Which cells represent a memory, and when are they engaged?

Clément Pouget, Flora Morier, Nadja Treiber, Pablo Fernández García, Nina Mazza, Run Zhang, Isaiah Reeves, Stephen Winston, Mark A. Brimble, Christina K. Kim, Gisella Vetere. Deconstruction of a memory engram reveals distinct ensembles recruited at learning. bioRxiv 2024.12.11.627894; doi: …

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How the brain integrate recent experiences into existing memories ensures that memories contain the most recently available information?

Zaki, Y., Pennington, Z.T., Morales-Rodriguez, D. et al. Offline ensemble co-reactivation links memories across days. Nature (2024). https://doi.org/10.1038/s41586-024-08168-4

Abstract
“Memories are encoded in neural ensembles during learning1,2,3,4,5,6 and are stabilized by post-learning reactivation7,8,9,10,11,12,13,14,15,16,17. Integrating recent experiences into existing memories

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How learning-associated astrocyte ensembles regulate memory recall?

Williamson, M.R., Kwon, W., Woo, J. et al. Learning-associated astrocyte ensembles regulate memory recall. Nature (2024). https://doi.org/10.1038/s41586-024-08170-w

Abstract
The physical manifestations of memory formation and recall are fundamental questions that remain unresolved1. At the cellular level, ensembles …

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What are the mechanisms of memory-supporting neuronal dynamics in hippocampal area CA3?

Li, Yiding, John J. Briguglio, Sandro Romani, Jeffrey C. Magee, Eddy Kinganda-Lusamaki, Adrienne Amuri-Aziza, Nicolas Fernandez-Nuñez et al. “Mechanisms of memory-supporting neuronal dynamics in hippocampal area CA3.” Cell 187 (2024): 2030-2051.

 

Summary
Hippocampal CA3 is central to

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How memory and language are linked at the single-cell level?

D. E. Dijksterhuis et al. ,Pronouns reactivate conceptual representations in human hippocampal neurons.Science 385,1478-1484(2024).DOI:10.1126/science.adr2813

Abstract
“During discourse comprehension, every new word adds to an evolving representation of meaning that accumulates over consecutive sentences and constrains the next words

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How ants use latent learning without map-like representation of space to navigate?

Leo Clement, Sebastian Schwarz, Antoine Wystrach. Latent learning without map-like representation of space in navigating ants. bioRxiv 2024.08.29.610243; doi: https://doi.org/10.1101/2024.08.29.610243

Abstract
“Desert ants are excellent navigators. Each individual learns long foraging routes meandering between the trees and bushes in …

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How shifts in the composition of memory-encoding neuronal ensembles influence the evolution of a memory over time?

Vilde A. Kveim et al. ,Divergent recruitment of developmentally defined neuronal ensembles supports memory dynamics.Science 385,eadk0997(2024).DOI:10.1126/science.adk0997

Editor’s summary
Memories are not fixed; they evolve after encoding and their content can be updated upon changes in external or

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How the hippocampus supports episodic and spatial memory at the same time?

Alexander Nitsch, Naomi de Haas, Mona M. Garvert, Christian F. Doeller. Integrating episodic and spatial context signals in the hippocampus. bioRxiv 2024.06.24.600445; doi: https://doi.org/10.1101/2024.06.24.600445

Abstract
Episodic and spatial memory are the two key components of the mnemonic system

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