Category: Goal Representation

Whether the entorhinal grid system is also involved in predicting where an animal will be in the next moment?

Ayako Ouchi, Shigeyoshi Fujisawa ,Predictive grid coding in the medial entorhinal cortex.Science 385,776-784(2024).DOI:10.1126/science.ado4166

Editor’s summary
Grid cells in the entorhinal cortex create a coordinate system of the environment for spatial navigation. However, it is not clear whether

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How animals simultaneously map their surroundings and tether goals to these surroundings during early experience in a novel environment?

Dan, Chuntao, Brad K. Hulse, Ramya Kappagantula, Vivek Jayaraman and Ann M. Hermundstad. “A neural circuit architecture for rapid learning in goal-directed navigation.” Neuron (2024): DOI:https://doi.org/10.1016/j.neuron.2024.04.036

Summary
Anchoring goals to spatial representations enables flexible navigation but is

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How the hippocampus represents the temporal distance to different goals?

Alison Montagrin, Denise E. Croote, Maria Giulia Preti, Liron Lerman, Mark G. Baxter, Daniela Schiller. Hippocampal timestamp for goals
bioRxiv 2023.07.27.550892; doi: https://doi.org/10.1101/2023.07.27.550892

Abstract
Our brain must manage multiple goals that differ in their temporal proximity. Some …

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How hippocampal CA1 neurons encode both world-centered spatial information and animals’ location relative to the local landmarks, with a common directional input presumably provided by the head direction cell system?

Yue-Qing Zhou, Vyash Puliyadi, Xiaojing Chen, Joonhee Leo Lee, Lan-Yuan Zhang, James J. Knierim. Conjunctive vector coding and place coding in hippocampus share a common directional signal. bioRxiv 2023.06.02.543340; doi: https://doi.org/10.1101/2023.06.02.543340

Abstract
Vector coding is becoming increasingly understood

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How contextual and goal information are incorporated in the construction and execution of navigational plans in the human hippocampus?

Jordan Crivelli-Decker, Alex Clarke, Seongmin A. Park, Derek J. Huffman, Erie D. Boorman & Charan Ranganath. Goal-oriented representations in the human hippocampus during planning and navigation. Nat Commun 14, 2946 (2023). https://doi.org/10.1038/s41467-023-35967-6

Abstract
“Recent work in cognitive and systems …

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How to convert an allocentric goal into an egocentric steering signal?

Peter Mussells Pires, L.F. Abbott, Gaby Maimon. Converting an allocentric goal into an egocentric steering signal. bioRxiv 2022.11.10.516026; doi: https://doi.org/10.1101/2022.11.10.516026

Abstract
Neuronal signals relevant for spatial navigation have been described in many species1–12, however, a circuit-level understanding of

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How the neural representation of allocentric space is distorted by goal-directed behaviour?

PS Muhle-Karbe, H Sheahan, G Pezzulo, HJ Spiers, S Chien, NW Schuck, C Summerfield. Goal-seeking compresses neural codes for space in the human hippocampus and orbitofrontal cortex. bioRxiv 2023.01.12.523762; doi: https://doi.org/10.1101/2023.01.12.523762

Abstract
Humans can navigate flexibly to meet

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How the escape circuit incorporates spatial information to execute rapid flights along the most efficient route to shelter?

Dario Campagner, Ruben Vale, Yu Lin Tan, Panagiota Iordanidou, Oriol Pavón Arocas, Federico Claudi, A. Vanessa Stempel, Sepiedeh Keshavarzi, Rasmus S. Petersen, Troy W. Margrie & Tiago Branco. A cortico-collicular circuit for orienting to shelter during escapeNature (2022). …

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How neurons encode variables during goal-directed navigation in environments that dynamically change?

Alexander Gonzalez, Lisa M Giocomo. Parahippocampal neurons encode task-relevant information for goal-directed navigation. bioRxiv 2022.12.15.520660; doi: https://doi.org/10.1101/2022.12.15.520660

Abstract
“A behavioral strategy crucial to survival is directed navigation to a goal, such as a food or home location. One potential

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How does the brain transform a head direction signal into a goal-oriented steering command?

Elena A. Westeinde, Emily Kellogg, Paul M. Dawson, Jenny Lu, Lydia Hamburg, Benjamin Midler, Shaul Druckmann, Rachel I. Wilson. Transforming a head direction signal into a goal-oriented steering command. bioRxiv 2022.11.10.516039; doi: https://doi.org/10.1101/2022.11.10.516039

Abstract
To navigate, we must

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How does the monarch butterfly brain encode goal direction?

M. Jerome Beetz, Christian Kraus, Basil el Jundi. Neural representation of goal direction in the monarch butterfly brain. bioRxiv 2022.10.15.512348; doi: https://doi.org/10.1101/2022.10.15.512348

Abstract
Neural processing of a navigational goal requires the continuous comparison between the current heading and

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How do hippocampal replays adapt to spatial contingency changes?

John Widloski, David J. Foster. Flexible rerouting of hippocampal replay sequences around changing barriers in the absence of global place field remapping. Neuron, 2022, 110, 1–12.

Summary
“Flexibility is a hallmark of memories that depend on the hippocampus. For

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How does the mammalian brain represent goal locations?

Nils Nyberg, Éléonore Duvelle, Caswell Barry, Hugo J. Spiers. Spatial goal coding in the hippocampal formation. Neuron, January 14, 2022. DOI:https://doi.org/10.1016/j.neuron.2021.12.012

Summary
“The mammalian hippocampal formation contains several distinct populations of neurons involved in representing self-position and orientation. These …

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