Tag: Hippocampus

How human hippocampal ripples coordinate planning sequences and compositional representations in neocortex?

Li He, Xiongfei Wang, Jinbo Zhang, Zhibing Xiao, Xiangyu Hu, Philipp Schwartenbeck, Jacob Bakermans, Tim Behrens & Yunzhe Liu. Human hippocampal ripples coordinate planning sequences and compositional representations in neocortex. Nat Neurosci (2026). https://doi.org/10.1038/s41593-026-02291-3

Abstract
“The human …

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What’s the replay and representation dynamics in the hippocampus of freely flying bats?

Angelo Forli, Wudi Fan, Kevin K. Qi & Michael M. Yartsev. Replay and representation dynamics in the hippocampus of freely flying bats. Nature (2025). https://doi.org/10.1038/s41586-025-09341-z

Abstract
“Cognitive functions for navigation and memory rely on emergent properties of …

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How brain networks connected by labile synapses store new information without catastrophically overwriting previous memories?

Sachin P. Vaidya, Guanchun Li, Raymond A. Chitwood, Yiding Li & Jeffrey C. Magee. Formation of an expanding memory representation in the hippocampus. Nat Neurosci (2025). https://doi.org/10.1038/s41593-025-01986-3

Abstract
“How brain networks connected by labile synapses store new information …

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How are memories formed and stored in the brain?

Marco Uytiepo†, Yongchuan Zhu†, Eric Bushong, Katherine Chou, Filip Souza Polli, Elise Zhao,Keun-Young Kim, Danielle Luu, Lyanne Chang, Dong Yang, Tsz Ching Ma, Mingi Kim, Yuting Zhang,Grant Walton, Tom Quach, Matthias Haberl, Luca Patapoutian, Arya Shahbazi, Yuxuan Zhang,Elizabeth Beutter, Weiheng …

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What’s human neural dynamics of real-world and imagined navigation?

Martin Seeber, Matthias Stangl, Mauricio Vallejo Martelo, Uros Topalovic, Sonja Hiller, Casey H. Halpern, Jean-Philippe Langevin, Vikram R. Rao, Itzhak Fried, Dawn Eliashiv & Nanthia Suthana. Human neural dynamics of real-world and imagined navigation. Nat Hum Behav (2025). https://doi.org/10.1038/s41562-025-02119-3…

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How learning produces an orthogonalized state machine in the hippocampus?

Sun, W., Winnubst, J., Natrajan, M. et al. Learning produces an orthogonalized state machine in the hippocampus. Nature (2025). https://doi.org/10.1038/s41586-024-08548-w

Abstract
“Cognitive maps confer animals with flexible intelligence by representing spatial, temporal and abstract relationships that can be …

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How does one brain circuit encode memories of both places and events?

Sarthak Chandra, Sugandha Sharma, Rishidev Chaudhuri & Ila Fiete. Episodic and associative memory from spatial scaffolds in the hippocampus. Nature (2025). https://doi.org/10.1038/s41586-024-08392-y

Abstract
“Hippocampal circuits in the brain enable two distinct cognitive functions: the construction of spatial maps for …

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How learning-associated astrocyte ensembles regulate memory recall?

Williamson, M.R., Kwon, W., Woo, J. et al. Learning-associated astrocyte ensembles regulate memory recall. Nature (2024). https://doi.org/10.1038/s41586-024-08170-w

Abstract
“The physical manifestations of memory formation and recall are fundamental questions that remain unresolved1. At the cellular level, ensembles …

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How the hippocampus supports episodic and spatial memory at the same time?

Alexander Nitsch, Naomi de Haas, Mona M. Garvert, Christian F. Doeller. Integrating episodic and spatial context signals in the hippocampus. bioRxiv 2024.06.24.600445; doi: https://doi.org/10.1101/2024.06.24.600445

Abstract
“Episodic and spatial memory are the two key components of the mnemonic system …

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Whether and how neural dynamics of hippocampal neurons are influenced by the presence and actions of human experimenters?

Snyder, M.C., Qi, K.K. & Yartsev, M.M. Neural representation of human experimenters in the bat hippocampus. Nat Neurosci (2024). https://doi.org/10.1038/s41593-024-01690-8

Abstract
“Here we conducted wireless electrophysiological recording of hippocampal neurons from Egyptian fruit bats in the presence of human …

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How the hippocampus represents different spaces?

Fenton, A.A. Remapping revisited: how the hippocampus represents different spaces. Nat. Rev. Neurosci. (2024). https://doi.org/10.1038/s41583-024-00817-x

Abstract
“The representation of distinct spaces by hippocampal place cells has been linked to changes in their place fields (the locations in the …

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How to implement distinct manifold encoding of navigational information in the subiculum and hippocampus?

Shinya Nakai, Takuma Kitanishi, Kenji Mizuseki. Distinct manifold encoding of navigational information in the subiculum and hippocampus. Science Advances, 10,eadi4471(2024).DOI:10.1126/sciadv.adi4471

Abstract
“The subiculum (SUB) plays a crucial role in spatial navigation and encodes navigational information differently from the …

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How contextual and goal information are incorporated in the construction and execution of navigational plans in the human hippocampus?

Jordan Crivelli-Decker, Alex Clarke, Seongmin A. Park, Derek J. Huffman, Erie D. Boorman & Charan Ranganath. Goal-oriented representations in the human hippocampus during planning and navigation. Nat Commun 14, 2946 (2023). https://doi.org/10.1038/s41467-023-35967-6

Abstract
“Recent work in cognitive and systems …

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How are objects and landmarks encoded by the hippocampal neural population for navigation?

Anne Nagelhus, Sebastian O. Andersson, Soledad Gonzalo Cogno, Edvard I. Moser, May-Britt Moser. Object-centered population coding in CA1 of the hippocampus. Neuron 111, 1–14, 2023.

Summary
“Objects and landmarks are crucial for guiding navigation and must be integrated …

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How context recognition and heading retrieval are coded in CA1 and how these processes change with experience during spatial reorientation?

Celia M. Gagliardi, Marc E. Normandin, Alexandra T. Keinath, Joshua B. Julian, Matthew R. Lopez, Manuel-Miguel Ramos-Alvarez, Russell A. Epstein, and Isabel A. Muzzio. Distinct neural mechanisms for heading retrieval and context recognition in the hippocampus during spatial reorientation. …

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