Category: Cognitive Navigation

How tuft dendrites in frontal motor cortex enable flexible learning?

Eduardo Maristany de las Casas, Kris Killmann, Moritz Drüke, Lukas Münster, Christian Ebner,Robert Sachdev, Dieter Jaeger, Matthew E. Larkum. Tuft dendrites in frontal motor cortex enable flexible learning. Science 392, eadx4358(2026). DOI:10.1126/science.adx4358

Abstract
Flexible learning relies on integrating

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How human hippocampal ripples coordinate planning sequences and compositional representations in neocortex?

Li He, Xiongfei Wang, Jinbo Zhang, Zhibing Xiao, Xiangyu Hu, Philipp Schwartenbeck, Jacob Bakermans, Tim Behrens & Yunzhe Liu. Human hippocampal ripples coordinate planning sequences and compositional representations in neocortexNat Neurosci (2026). https://doi.org/10.1038/s41593-026-02291-3

Abstract
The human

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How to implement planning in the Brain?

Marcelo G. Mattar, Nathaniel D. Daw. Planning in the Brain: It’s Not What You Think It Is. Annual Review Neuroscience, 2026, 49.  https://doi.org/10.1146/annurev-neuro-102124-015847

Abstract
“The neuroscience of planning has long been analogized to search algorithms in artificial intelligence (AI), …

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How entorhinal cortex represent task-relevant remote locations independently of CA1?

Emily A. Aery Jones, Isabel I. C. Low, Frances S. Cho & Lisa M. Giocomo. Entorhinal cortex represents task-relevant remote locations independently of CA1. Nat Neurosci (2026). https://doi.org/10.1038/s41593-026-02232-0

Abstract
“Neurons can collectively represent the current sensory experience during exploration …

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How topographic CA1 input shape subicular spatial coding?

Yanjun Sun, Daniel T. Pederick, Xiangmin Xu, Liqun Luo, Lisa M. Giocomo. Topographic CA1 input shapes subicular spatial coding. bioRxiv 2026.03.24.714092; doi: https://doi.org/10.64898/2026.03.24.714092

Abstract
Topographic organization characterizes hippocampal circuits, yet its functional significance remains unclear. By selectively …

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How cross-scale dynamics are jointly organized in space and time, and how this spatiotemporal organization supports flexible hierarchical processing in the brain?

Harris, B., Gong, P. Nested spatiotemporal theta–gamma waves organize hierarchical processing across the mouse visual cortex. Nat Commun 17, 2629 (2026). https://doi.org/10.1038/s41467-026-68893-4

Abstract
The brain processes visual information across diverse spatial and temporal scales, but the dynamics that

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How does the brain’s “navigation circuit” operate in real-world conditions?

Palgi S., Ray S., Maimon S. R., Waserman Y., Ben-Ari L., Eliav T., Tuval A., Cohen C., Ali A. I., Keyyu J. D., Mouritsen H., Las L. & Ulanovsky N. Head-direction cells as a neural compass in bats navigating outdoors

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How locomotor development shapes hippocampal spatial coding?

Marco P. Abrate, Laurenz Muessig, Francesca Cacucci, Joshua P. Bassett, Hui Min Tan, Thomas J. Wills, Caswell Barry. From movement to cognitive maps: recurrent neural networks reveal how locomotor development shapes hippocampal spatial coding. bioRxiv 2025.12.30.696864; doi: https://doi.org/10.64898/2025.12.30.696864

Abstract…

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How human, animals, robots encode and recall place?

Michael Milford and Tobias Fischer. Going Places: Place Recognition in Artificial and Natural Systems. Annu. Rev. Control Robot. Auton. Syst. 2026. 9:7.1-7.27:1–28. https://doi.org/10.1146/annurev-control-032724-014418

Abstract

Place recognition—the ability to identify previously visited locations—is critical for both biological navigation and

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How the Hippocampal Cognitive Map Supports Flexible Navigation?

O’Keefe J. How the Hippocampal Cognitive Map Supports Flexible Navigation. Annual Review of Neuroscience. 2025 Apr 8;48.

ABSTRACT

“During navigation to a goal, a portion of the hippocampal place cells exhibit directional preferences, firing more in some directions than …

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How hippocampal representations drift in stable multisensory environments?

Climer, J.R., Davoudi, H., Oh, J.Y. et al. Hippocampal representations drift in stable multisensory environments. Nature 645, 457–465 (2025). https://doi.org/10.1038/s41586-025-09245-y

Abstract
“Experiments that track hippocampal place cells in mice navigating the same real environment have found significant changes in …

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How cooperative actions of interneuron families support the hippocampal spatial code?

Manuel Valero, Pablo Abad-Perez, Andrea Gallardo, Marta Picco, Raquel García-Hernandez, Jorge Brotons, Anel Martínez-Félix, Robert Machold, Bernardo Rudy, György Buzsáki. Cooperative actions of interneuron families support the hippocampal spatial code. Science 389,eadv5638(2025). DOI:10.1126/science.adv5638

Abstract
Identifying the computational roles

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How mice navigate scent trails using predictive policies?

Siddharth Jayakumar, Nicola Rigolli, Mackenzie W Mathis, Massimo Vergassola, Alexander Mathis, Venkatesh N Murthy. Mice navigate scent trails using predictive policies. bioRxiv 2025.08.27.672631; doi: https://doi.org/10.1101/2025.08.27.672631

Abstract
Animals actively sense their environment to extract features of interest to guide

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What’s the replay and representation dynamics in the hippocampus of freely flying bats?

Angelo Forli, Wudi Fan, Kevin K. Qi & Michael M. Yartsev. Replay and representation dynamics in the hippocampus of freely flying batsNature (2025). https://doi.org/10.1038/s41586-025-09341-z

Abstract
Cognitive functions for navigation and memory rely on emergent properties of

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How the brain coordinates remote vision with the activity of place cells?

Hannah L. Payne & Dmitriy Aronov. Remote activation of place codes by gaze in a highly visual animal. Nature (2025). https://doi.org/10.1038/s41586-025-09101-z

Abstract
Vision enables many animals to perform spatial reasoning from remote locations1. By viewing distant landmarks, …

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