Category: Cognitive Navigation

How does the brain update memory representation?

William Mau, Michael E Hasselmo, Denise J Cai. The brain in motion: How ensemble fluidity drives memory-updating and flexibility
eLife 2020;9:e63550 DOI: 10.7554/eLife.63550

Abstract
“While memories are often thought of as flashbacks to a previous experience, they do not …

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How do time cells in the human hippocampus and entorhinal cortex support episodic memory?

Gray Umbach, Pranish Kantak, Joshua Jacobs, Michael Kahana, Brad E. Pfeiffer, Michael Sperling, Bradley Lega. Time cells in the human hippocampus and entorhinal cortex support episodic memory. Proceedings of the National Academy of Sciences Nov 2020, 117 (45) 28463-28474; …

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How do hippocampal replay patterns dynamically change during the spatial learning process

Hideyoshi Igata, Yuji Ikegaya, Takuya Sasaki. Prioritized experience replays on a hippocampal predictive map for learning. Proceedings of the National Academy of Sciences Jan 2021, 118 (1) e2011266118; DOI: 10.1073/pnas.2011266118

Significance

The hippocampus is crucial for spatial learning

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How to implement sensory processing, learning, and motor control using a biologically spiking neural network model of the flying insect mushroom body?

Hannes Rapp, Martin Paul Nawrot. A spiking neural program for sensorimotor control during foraging in flying insects. Proceedings of the National Academy of Sciences Nov 2020, 117 (45) 28412-28421; DOI: 10.1073/pnas.2009821117

Significance

Living organisms demonstrate remarkable abilities in

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How does the brain integrate self-motion and goals adaptively?

Andrew S. Alexander, Janet C. Tung, G. William Chapman, Laura E. Shelley, Michael E. Hasselmo, Douglas A. Nitz. Adaptive integration of self-motion and goals in posterior parietal cortexbioRxiv 2020.12.19.423589; doi: https://doi.org/10.1101/2020.12.19.423589

Abstract
Animals engage in a variety

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How does the brain encode abstract state-space representations in high-dimensional environments?

Cross L, Cockburn J, Yue Y, O’Doherty JP. Using deep reinforcement learning to reveal how the brain encodes abstract state-space representations in high-dimensional environments. Neuron. 2020 Dec 7:S0896-6273(20)30899-0. doi: 10.1016/j.neuron.2020.11.021.

In Brief
Cross et al. scanned humans playing

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How does the monkey brain represent what and when conjunctively during anassociative memory task?

Cruzado NA, Tiganj Z, Brincat SL, Miller EK, Howard MW. Conjunctive representation of what and when in monkey hippocampus and lateral prefrontal cortex during an associative memory task. Hippocampus. 2020 Dec;30(12):1332-1346. doi: 10.1002/hipo.23282.

Abstract
Adaptive memory requires the

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